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Loss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activity.
Ou O, Huppi K, Chakka S, Gehlhaus K, Dubois W, Patel J, Chen J, Mackiewicz M, Jones TL, Pitt JJ, Martin SE, Goldsmith P, Simmons JK, Mock BA, Caplen NJ. Ou O, et al. Among authors: huppi k. Cancer Lett. 2014 Nov 28;354(2):336-47. doi: 10.1016/j.canlet.2014.08.043. Epub 2014 Sep 1. Cancer Lett. 2014. PMID: 25193464 Free PMC article.
MicroRNAs and genomic instability.
Huppi K, Volfovsky N, Mackiewicz M, Runfola T, Jones TL, Martin SE, Stephens R, Caplen NJ. Huppi K, et al. Semin Cancer Biol. 2007 Feb;17(1):65-73. doi: 10.1016/j.semcancer.2006.10.004. Epub 2006 Oct 26. Semin Cancer Biol. 2007. PMID: 17113784 Free PMC article. Review.
Defining and assaying RNAi in mammalian cells.
Huppi K, Martin SE, Caplen NJ. Huppi K, et al. Mol Cell. 2005 Jan 7;17(1):1-10. doi: 10.1016/j.molcel.2004.12.017. Mol Cell. 2005. PMID: 15629712 Free article. Review.
Multiplexing siRNAs to compress RNAi-based screen size in human cells.
Martin SE, Jones TL, Thomas CL, Lorenzi PL, Nguyen DA, Runfola T, Gunsior M, Weinstein JN, Goldsmith PK, Lader E, Huppi K, Caplen NJ. Martin SE, et al. Among authors: huppi k. Nucleic Acids Res. 2007;35(8):e57. doi: 10.1093/nar/gkm141. Epub 2007 Mar 28. Nucleic Acids Res. 2007. PMID: 17392344 Free PMC article.
119 results