High frequency of antitumor T cells in the blood of melanoma patients before and after vaccination with tumor antigens.
Germeau C, Ma W, Schiavetti F, Lurquin C, Henry E, Vigneron N, Brasseur F, Lethé B, De Plaen E, Velu T, Boon T, Coulie PG.
Germeau C, et al. Among authors: boon t.
J Exp Med. 2005 Jan 17;201(2):241-8. doi: 10.1084/jem.20041379.
J Exp Med. 2005.
PMID: 15657293
Free PMC article.
After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression, the frequency of anti-vaccine T cells in the blood was often either undetectable or <10(-5) of CD8 T cells. ...Lethe, V. Corbiere, I. Th …
After vaccination of melanoma patients with MAGE antigens, we observed that even in the few patients showing tumor regression, the frequency …