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Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
Handratta VD, Vasaitis TS, Njar VC, Gediya LK, Kataria R, Chopra P, Newman D Jr, Farquhar R, Guo Z, Qiu Y, Brodie AM. Handratta VD, et al. Among authors: chopra p. J Med Chem. 2005 Apr 21;48(8):2972-84. doi: 10.1021/jm040202w. J Med Chem. 2005. PMID: 15828836
Retinoids in clinical use.
Njar VC, Gediya L, Purushottamachar P, Chopra P, Belosay A, Patel JB. Njar VC, et al. Among authors: chopra p. Med Chem. 2006 Jul;2(4):431-8. doi: 10.2174/157340606777724022. Med Chem. 2006. PMID: 16848757 Review.
Androgen receptor inactivation contributes to antitumor efficacy of 17{alpha}-hydroxylase/17,20-lyase inhibitor 3beta-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene in prostate cancer.
Vasaitis T, Belosay A, Schayowitz A, Khandelwal A, Chopra P, Gediya LK, Guo Z, Fang HB, Njar VC, Brodie AM. Vasaitis T, et al. Among authors: chopra p. Mol Cancer Ther. 2008 Aug;7(8):2348-57. doi: 10.1158/1535-7163.MCT-08-0230. Mol Cancer Ther. 2008. PMID: 18723482 Free PMC article.
Case-control meta-analysis of blood DNA methylation and autism spectrum disorder.
Andrews SV, Sheppard B, Windham GC, Schieve LA, Schendel DE, Croen LA, Chopra P, Alisch RS, Newschaffer CJ, Warren ST, Feinberg AP, Fallin MD, Ladd-Acosta C. Andrews SV, et al. Among authors: chopra p. Mol Autism. 2018 Jun 28;9:40. doi: 10.1186/s13229-018-0224-6. eCollection 2018. Mol Autism. 2018. PMID: 29988321 Free PMC article.
Age-associated DNA methylation in pediatric populations.
Alisch RS, Barwick BG, Chopra P, Myrick LK, Satten GA, Conneely KN, Warren ST. Alisch RS, et al. Among authors: chopra p. Genome Res. 2012 Apr;22(4):623-32. doi: 10.1101/gr.125187.111. Epub 2012 Feb 1. Genome Res. 2012. PMID: 22300631 Free PMC article.
562 results