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Multiple repair pathways mediate tolerance to chemotherapeutic cross-linking agents in vertebrate cells.
Nojima K, Hochegger H, Saberi A, Fukushima T, Kikuchi K, Yoshimura M, Orelli BJ, Bishop DK, Hirano S, Ohzeki M, Ishiai M, Yamamoto K, Takata M, Arakawa H, Buerstedde JM, Yamazoe M, Kawamoto T, Araki K, Takahashi JA, Hashimoto N, Takeda S, Sonoda E. Nojima K, et al. Among authors: saberi a. Cancer Res. 2005 Dec 15;65(24):11704-11. doi: 10.1158/0008-5472.CAN-05-1214. Cancer Res. 2005. PMID: 16357182
RAD18 and poly(ADP-ribose) polymerase independently suppress the access of nonhomologous end joining to double-strand breaks and facilitate homologous recombination-mediated repair.
Saberi A, Hochegger H, Szuts D, Lan L, Yasui A, Sale JE, Taniguchi Y, Murakawa Y, Zeng W, Yokomori K, Helleday T, Teraoka H, Arakawa H, Buerstedde JM, Takeda S. Saberi A, et al. Mol Cell Biol. 2007 Apr;27(7):2562-71. doi: 10.1128/MCB.01243-06. Epub 2007 Jan 22. Mol Cell Biol. 2007. PMID: 17242200 Free PMC article.
The 9-1-1 DNA clamp is required for immunoglobulin gene conversion.
Saberi A, Nakahara M, Sale JE, Kikuchi K, Arakawa H, Buerstedde JM, Yamamoto K, Takeda S, Sonoda E. Saberi A, et al. Mol Cell Biol. 2008 Oct;28(19):6113-22. doi: 10.1128/MCB.00156-08. Epub 2008 Jul 28. Mol Cell Biol. 2008. PMID: 18662998 Free PMC article.
Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity.
Smith S, Fox J, Mejia M, Ruangpradit W, Saberi A, Kim S, Choi Y, Oh S, Wang Y, Choi K, Li L, Hendrickson EA, Takeda S, Muller M, Myung K. Smith S, et al. Among authors: saberi a. PLoS One. 2014 Jan 23;9(1):e87203. doi: 10.1371/journal.pone.0087203. eCollection 2014. PLoS One. 2014. PMID: 24466340 Free PMC article.
FANCI phosphorylation functions as a molecular switch to turn on the Fanconi anemia pathway.
Ishiai M, Kitao H, Smogorzewska A, Tomida J, Kinomura A, Uchida E, Saberi A, Kinoshita E, Kinoshita-Kikuta E, Koike T, Tashiro S, Elledge SJ, Takata M. Ishiai M, et al. Among authors: saberi a. Nat Struct Mol Biol. 2008 Nov;15(11):1138-46. doi: 10.1038/nsmb.1504. Epub 2008 Oct 19. Nat Struct Mol Biol. 2008. PMID: 18931676 Free PMC article.
248 results