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The low density lipoprotein receptor-related protein (LRP) is a novel beta-secretase (BACE1) substrate.
von Arnim CA, Kinoshita A, Peltan ID, Tangredi MM, Herl L, Lee BM, Spoelgen R, Hshieh TT, Ranganathan S, Battey FD, Liu CX, Bacskai BJ, Sever S, Irizarry MC, Strickland DK, Hyman BT. von Arnim CA, et al. Among authors: hyman bt. J Biol Chem. 2005 May 6;280(18):17777-85. doi: 10.1074/jbc.M414248200. Epub 2005 Mar 4. J Biol Chem. 2005. PMID: 15749709 Free article.
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Andersen OM, Reiche J, Schmidt V, Gotthardt M, Spoelgen R, Behlke J, von Arnim CA, Breiderhoff T, Jansen P, Wu X, Bales KR, Cappai R, Masters CL, Gliemann J, Mufson EJ, Hyman BT, Paul SM, Nykjaer A, Willnow TE. Andersen OM, et al. Among authors: hyman bt. Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13461-6. doi: 10.1073/pnas.0503689102. Epub 2005 Sep 7. Proc Natl Acad Sci U S A. 2005. PMID: 16174740 Free PMC article.
Formation of toxic oligomeric alpha-synuclein species in living cells.
Outeiro TF, Putcha P, Tetzlaff JE, Spoelgen R, Koker M, Carvalho F, Hyman BT, McLean PJ. Outeiro TF, et al. Among authors: hyman bt. PLoS One. 2008 Apr 2;3(4):e1867. doi: 10.1371/journal.pone.0001867. PLoS One. 2008. PMID: 18382657 Free PMC article.
The LDL receptor-related protein can form homo-dimers in neuronal cells.
Makarova A, Bercury KK, Adams KW, Joyner D, Deng M, Spoelgen R, Koker M, Strickland DK, Hyman BT. Makarova A, et al. Among authors: hyman bt. Neurosci Lett. 2008 Sep 12;442(2):91-5. doi: 10.1016/j.neulet.2008.06.070. Epub 2008 Jun 28. Neurosci Lett. 2008. PMID: 18602448 Free PMC article.
831 results