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A simple structural-based approach to prevent aminoglycoside inactivation by bacterial defense proteins. Conformational restriction provides effective protection against neomycin-B nucleotidylation by ANT4.
Asensio JL, Hidalgo A, Bastida A, Torrado M, Corzana F, Chiara JL, García-Junceda E, Cañada J, Jiménez-Barbero J. Asensio JL, et al. Among authors: chiara jl. J Am Chem Soc. 2005 Jun 15;127(23):8278-9. doi: 10.1021/ja051722z. J Am Chem Soc. 2005. PMID: 15941249 Free article.
Experimental evidence for the existence of non-exo-anomeric conformations in branched oligosaccharides: NMR analysis of the structure and dynamics of aminoglycosides of the neomycin family.
Asensio JL, Hidalgo A, Cuesta I, González C, Cañada J, Vicent C, Chiara JL, Cuevas G, Jiménez-Barbero J. Asensio JL, et al. Among authors: chiara jl. Chemistry. 2002 Nov 15;8(22):5228-40. doi: 10.1002/1521-3765(20021115)8:22<5228::AID-CHEM5228>3.0.CO;2-L. Chemistry. 2002. PMID: 12613042
Shedding light on the mitochondrial matrix through a functional membrane transporter.
Blázquez-Moraleja A, Sáenz-de-Santa María I, Chiara MD, Álvarez-Fernández D, García-Moreno I, Prieto-Montero R, Martínez-Martínez V, López Arbeloa I, Chiara JL. Blázquez-Moraleja A, et al. Among authors: chiara jl. Chem Sci. 2019 Dec 9;11(4):1052-1065. doi: 10.1039/c9sc04852a. Chem Sci. 2019. PMID: 34084361 Free PMC article.
26 results