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3Beta-alkyl-androsterones as inhibitors of type 3 17beta-hydroxysteroid dehydrogenase: inhibitory potency in intact cells, selectivity towards isoforms 1, 2, 5 and 7, binding affinity for steroid receptors, and proliferative/antiproliferative activities on AR+ and ER+ cell lines.
Mol Cell Endocrinol. 2006 Mar 27;248(1-2):225-32. doi: 10.1016/j.mce.2005.10.023. Epub 2005 Dec 15.
Mol Cell Endocrinol. 2006.
PMID: 16359782
Androsterone 3beta-substituted derivatives as inhibitors of type 3 17beta-hydroxysteroid dehydrogenase.
Ngatcha BT, Luu-The V, Poirier D.
Ngatcha BT, et al.
Bioorg Med Chem Lett. 2000 Nov 20;10(22):2533-6. doi: 10.1016/s0960-894x(00)00517-5.
Bioorg Med Chem Lett. 2000.
PMID: 11086723
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Synthesis of 5α-androstane-17-spiro-δ-lactones with a 3-keto, 3-hydroxy, 3-spirocarbamate or 3-spiromorpholinone as inhibitors of 17β-hydroxysteroid dehydrogenases.
Djigoué GB, Ngatcha BT, Roy J, Poirier D.
Djigoué GB, et al. Among authors: ngatcha bt.
Molecules. 2013 Jan 11;18(1):914-33. doi: 10.3390/molecules18010914.
Molecules. 2013.
PMID: 23344201
Free PMC article.
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D-ring allyl derivatives of 17 beta- and 17 alpha-estradiols: chemical synthesis and 13C NMR data.
Dionne P, Ngatcha BT, Poirier D.
Dionne P, et al. Among authors: ngatcha bt.
Steroids. 1997 Oct;62(10):674-81. doi: 10.1016/s0039-128x(97)00067-6.
Steroids. 1997.
PMID: 9381515
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