Hruby DE - Search Results

1

Identification and characterization of potent small molecule inhibitor of hemorrhagic fever New World arenaviruses.

Bolken TC, Laquerre S, Zhang Y, Bailey TR, Pevear DC, Kickner SS, Sperzel LE, Jones KF, Warren TK, Amanda Lund S, Kirkwood-Watts DL, King DS, Shurtleff AC, Guttieri MC, Deng Y, Bleam M, Hruby DE. Bolken TC, et al. Among authors: hruby de. Antiviral Res. 2006 Feb;69(2):86-97. doi: 10.1016/j.antiviral.2005.10.008. Epub 2005 Nov 28. Antiviral Res. 2006. PMID: 16343651 Free PMC article.

2

Discovery and development of antiviral drugs for biodefense: experience of a small biotechnology company.

Bolken TC, Hruby DE. Bolken TC, et al. Among authors: hruby de. Antiviral Res. 2008 Jan;77(1):1-5. doi: 10.1016/j.antiviral.2007.07.003. Epub 2007 Aug 15. Antiviral Res. 2008. PMID: 17765333 Free PMC article. Review.

3

Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination.

Grosenbach DW, Jordan R, King DS, Berhanu A, Warren TK, Kirkwood-Watts DL, Tyavanagimatt S, Tan Y, Wilson RL, Jones KF, Hruby DE. Grosenbach DW, et al. Among authors: hruby de. Vaccine. 2008 Feb 13;26(7):933-46. doi: 10.1016/j.vaccine.2007.11.095. Epub 2007 Dec 26. Vaccine. 2008. PMID: 18226434 Free PMC article.

4

Identification of a broad-spectrum arenavirus entry inhibitor.

Larson RA, Dai D, Hosack VT, Tan Y, Bolken TC, Hruby DE, Amberg SM. Larson RA, et al. Among authors: hruby de. J Virol. 2008 Nov;82(21):10768-75. doi: 10.1128/JVI.00941-08. Epub 2008 Aug 20. J Virol. 2008. PMID: 18715909 Free PMC article.

5

ST-246 inhibits in vivo poxvirus dissemination, virus shedding, and systemic disease manifestation.

Berhanu A, King DS, Mosier S, Jordan R, Jones KF, Hruby DE, Grosenbach DW. Berhanu A, et al. Among authors: hruby de. Antimicrob Agents Chemother. 2009 Dec;53(12):4999-5009. doi: 10.1128/AAC.00678-09. Epub 2009 Sep 14. Antimicrob Agents Chemother. 2009. PMID: 19752270 Free PMC article.

6

Evaluation of Lassa antiviral compound ST-193 in a guinea pig model.

Cashman KA, Smith MA, Twenhafel NA, Larson RA, Jones KF, Allen RD 3rd, Dai D, Chinsangaram J, Bolken TC, Hruby DE, Amberg SM, Hensley LE, Guttieri MC. Cashman KA, et al. Among authors: hruby de. Antiviral Res. 2011 Apr;90(1):70-9. doi: 10.1016/j.antiviral.2011.02.012. Epub 2011 Mar 1. Antiviral Res. 2011. PMID: 21371508 Free PMC article.

7

Tecovirimat for smallpox infections.

Bolken TC, Hruby DE. Bolken TC, et al. Among authors: hruby de. Drugs Today (Barc). 2010 Feb;46(2):109-17. doi: 10.1358/dot.2010.46.2.1437244. Drugs Today (Barc). 2010. PMID: 20393639

8

Analysis of factors affecting surface expression and immunogenicity of recombinant proteins expressed by gram-positive commensal vectors.

Bolken TC, Franke CA, Jones KF, Bell RH, Swanson RM, King DS, Fischetti VA, Hruby DE. Bolken TC, et al. Among authors: hruby de. Infect Immun. 2002 May;70(5):2487-91. doi: 10.1128/IAI.70.5.2487-2491.2002. Infect Immun. 2002. PMID: 11953386 Free PMC article.

9

Development of PLEX, a plasmid-based expression system for production of heterologous gene products by the gram-positive bacteria Streptococcus gordonii.

Warren TK, Lund SA, Jones KF, Hruby DE. Warren TK, et al. Among authors: hruby de. Protein Expr Purif. 2005 Apr;40(2):319-26. doi: 10.1016/j.pep.2004.10.019. Protein Expr Purif. 2005. PMID: 15766873

10

Listeria monocytogenes 10403S HtrA is necessary for resistance to cellular stress and virulence.

Wilson RL, Brown LL, Kirkwood-Watts D, Warren TK, Lund SA, King DS, Jones KF, Hruby DE. Wilson RL, et al. Among authors: hruby de. Infect Immun. 2006 Jan;74(1):765-8. doi: 10.1128/IAI.74.1.765-768.2006. Infect Immun. 2006. PMID: 16369036 Free PMC article.

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