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Glucosamine-induced phosphorylation of the alpha-subunit of eukaryotic initiation factor 2 is mediated by the protein kinase R-like endoplasmic-reticulum associated kinase.
Int J Biochem Cell Biol. 2006;38(5-6):1004-14. doi: 10.1016/j.biocel.2005.10.015. Epub 2005 Nov 16.
Int J Biochem Cell Biol. 2006.
PMID: 16324875
Ablation of 4E-BP1/2 prevents hyperglycemia-mediated induction of VEGF expression in the rodent retina and in Muller cells in culture.
Schrufer TL, Antonetti DA, Sonenberg N, Kimball SR, Gardner TW, Jefferson LS.
Schrufer TL, et al.
Diabetes. 2010 Sep;59(9):2107-16. doi: 10.2337/db10-0148. Epub 2010 Jun 14.
Diabetes. 2010.
PMID: 20547975
Free PMC article.
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Hyperglycemia-induced O-GlcNAcylation and truncation of 4E-BP1 protein in liver of a mouse model of type 1 diabetes.
Dennis MD, Schrufer TL, Bronson SK, Kimball SR, Jefferson LS.
Dennis MD, et al. Among authors: schrufer tl.
J Biol Chem. 2011 Sep 30;286(39):34286-97. doi: 10.1074/jbc.M111.259457. Epub 2011 Aug 12.
J Biol Chem. 2011.
PMID: 21840999
Free PMC article.
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