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Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease.
Chen Y, Shi-Wen X, van Beek J, Kennedy L, McLeod M, Renzoni EA, Bou-Gharios G, Wilcox-Adelman S, Goetinck PF, Eastwood M, Black CM, Abraham DJ, Leask A. Chen Y, et al. Among authors: renzoni ea. Am J Pathol. 2005 Dec;167(6):1699-711. doi: 10.1016/s0002-9440(10)61252-7. Am J Pathol. 2005. PMID: 16314481 Free PMC article.
Interstitial vascularity in fibrosing alveolitis.
Renzoni EA, Walsh DA, Salmon M, Wells AU, Sestini P, Nicholson AG, Veeraraghavan S, Bishop AE, Romanska HM, Pantelidis P, Black CM, Du Bois RM. Renzoni EA, et al. Am J Respir Crit Care Med. 2003 Feb 1;167(3):438-43. doi: 10.1164/rccm.200202-135OC. Epub 2002 Oct 3. Am J Respir Crit Care Med. 2003. PMID: 12406847
Endothelin-1 promotes myofibroblast induction through the ETA receptor via a rac/phosphoinositide 3-kinase/Akt-dependent pathway and is essential for the enhanced contractile phenotype of fibrotic fibroblasts.
Shi-Wen X, Chen Y, Denton CP, Eastwood M, Renzoni EA, Bou-Gharios G, Pearson JD, Dashwood M, du Bois RM, Black CM, Leask A, Abraham DJ. Shi-Wen X, et al. Among authors: renzoni ea. Mol Biol Cell. 2004 Jun;15(6):2707-19. doi: 10.1091/mbc.e03-12-0902. Epub 2004 Mar 26. Mol Biol Cell. 2004. PMID: 15047866 Free PMC article.
Gene expression profiling reveals novel TGFbeta targets in adult lung fibroblasts.
Renzoni EA, Abraham DJ, Howat S, Shi-Wen X, Sestini P, Bou-Gharios G, Wells AU, Veeraraghavan S, Nicholson AG, Denton CP, Leask A, Pearson JD, Black CM, Welsh KI, du Bois RM. Renzoni EA, et al. Respir Res. 2004 Nov 30;5(1):24. doi: 10.1186/1465-9921-5-24. Respir Res. 2004. PMID: 15571627 Free PMC article.
Activation of key profibrotic mechanisms in transgenic fibroblasts expressing kinase-deficient type II Transforming growth factor-{beta} receptor (T{beta}RII{delta}k).
Denton CP, Lindahl GE, Khan K, Shiwen X, Ong VH, Gaspar NJ, Lazaridis K, Edwards DR, Leask A, Eastwood M, Leoni P, Renzoni EA, Bou Gharios G, Abraham DJ, Black CM. Denton CP, et al. Among authors: renzoni ea. J Biol Chem. 2005 Apr 22;280(16):16053-65. doi: 10.1074/jbc.M413134200. Epub 2005 Feb 11. J Biol Chem. 2005. PMID: 15708853 Free article.
CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts.
Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton RJ, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, Leask A. Shi-wen X, et al. Among authors: renzoni ea. J Biol Chem. 2006 Apr 21;281(16):10715-26. doi: 10.1074/jbc.M511343200. Epub 2006 Feb 16. J Biol Chem. 2006. PMID: 16484225 Free article.
192 results