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Mortality and morbidity remain high despite captopril and/or Valsartan therapy in elderly patients with left ventricular systolic dysfunction, heart failure, or both after acute myocardial infarction: results from the Valsartan in Acute Myocardial Infarction Trial (VALIANT).
White HD, Aylward PE, Huang Z, Dalby AJ, Weaver WD, Barvik S, Marin-Neto JA, Murin J, Nordlander RO, van Gilst WH, Zannad F, McMurray JJ, Califf RM, Pfeffer MA; VALIANT Investigators. White HD, et al. Among authors: pfeffer ma. Circulation. 2005 Nov 29;112(22):3391-9. doi: 10.1161/CIRCULATIONAHA.105.551143. Epub 2005 Nov 21. Circulation. 2005. PMID: 16301343 Clinical Trial.
Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators.
Pfeffer MA, Braunwald E, Moyé LA, Basta L, Brown EJ Jr, Cuddy TE, Davis BR, Geltman EM, Goldman S, Flaker GC, et al. Pfeffer MA, et al. N Engl J Med. 1992 Sep 3;327(10):669-77. doi: 10.1056/NEJM199209033271001. N Engl J Med. 1992. PMID: 1386652 Free article. Clinical Trial.
Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril.
St John Sutton M, Pfeffer MA, Plappert T, Rouleau JL, Moyé LA, Dagenais GR, Lamas GA, Klein M, Sussex B, Goldman S, et al. St John Sutton M, et al. Among authors: pfeffer ma. Circulation. 1994 Jan;89(1):68-75. doi: 10.1161/01.cir.89.1.68. Circulation. 1994. PMID: 8281697 Clinical Trial.
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