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Diverse fibrillar peptides directly bind the Alzheimer's amyloid precursor protein and amyloid precursor-like protein 2 resulting in cellular accumulation.
White AR, Maher F, Brazier MW, Jobling MF, Thyer J, Stewart LR, Thompson A, Gibson R, Masters CL, Multhaup G, Beyreuther K, Barrow CJ, Collins SJ, Cappai R. White AR, et al. Among authors: multhaup g. Brain Res. 2003 Mar 21;966(2):231-44. doi: 10.1016/s0006-8993(02)04173-2. Brain Res. 2003. PMID: 12618346
Structure of the Alzheimer's disease amyloid precursor protein copper binding domain. A regulator of neuronal copper homeostasis.
Barnham KJ, McKinstry WJ, Multhaup G, Galatis D, Morton CJ, Curtain CC, Williamson NA, White AR, Hinds MG, Norton RS, Beyreuther K, Masters CL, Parker MW, Cappai R. Barnham KJ, et al. Among authors: multhaup g. J Biol Chem. 2003 May 9;278(19):17401-7. doi: 10.1074/jbc.M300629200. Epub 2003 Feb 28. J Biol Chem. 2003. PMID: 12611883 Free article.
Evidence for a copper-binding superfamily of the amyloid precursor protein.
Simons A, Ruppert T, Schmidt C, Schlicksupp A, Pipkorn R, Reed J, Masters CL, White AR, Cappai R, Beyreuther K, Bayer TA, Multhaup G. Simons A, et al. Among authors: multhaup g. Biochemistry. 2002 Jul 30;41(30):9310-20. doi: 10.1021/bi0258647. Biochemistry. 2002. PMID: 12135352
Suppression of amyloid beta A11 antibody immunoreactivity by vitamin C: possible role of heparan sulfate oligosaccharides derived from glypican-1 by ascorbate-induced, nitric oxide (NO)-catalyzed degradation.
Cheng F, Cappai R, Ciccotosto GD, Svensson G, Multhaup G, Fransson LÅ, Mani K. Cheng F, et al. Among authors: multhaup g. J Biol Chem. 2011 Aug 5;286(31):27559-72. doi: 10.1074/jbc.M111.243345. Epub 2011 Jun 3. J Biol Chem. 2011. PMID: 21642435 Free PMC article.
208 results