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Methotrexate inhibition of SARS-CoV-2 entry, infection and inflammation revealed by bioinformatics approach and a hamster model.
Chen YT, Chang YH, Pathak N, Tzou SC, Luo YC, Hsu YC, Li TN, Lee JY, Chen YC, Huang YW, Yang HJ, Hsu NY, Tsai HP, Chang TY, Hsu SC, Liu PC, Chin YF, Lin WC, Yang CM, Wu HL, Lee CY, Hsu HL, Liu YC, Chu JW, Wang LH, Wang JY, Huang CH, Lin CH, Hsieh PS, Wu Lee YH, Hung YJ, Yang JM. Chen YT, et al. Among authors: yang hj, yang jm, yang cm. Front Immunol. 2022 Dec 21;13:1080897. doi: 10.3389/fimmu.2022.1080897. eCollection 2022. Front Immunol. 2022. PMID: 36618412 Free PMC article.
BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase inhibitor, inhibits SARS-CoV-2 variants of concern and exerts synergistic antiviral activity in combination with remdesivir.
Tang W-F, Chang Y-H, Lin C-C, Jheng J-R, Hsieh C-F, Chin Y-F, Chang T-Y, Lee J-C, Liang P-H, Lin C-Y, Lin G-H, Cai J-Y, Chen Y-L, Chen Y-S, Tsai S-K, Liu P-C, Yang C-M, Shadbahr T, Tang J, Hsu Y-L, Huang C-H, Wang L-Y, Chen CC, Kau J-H, Hung Y-J, Lee H-Y, Wang W-C, Tsai H-P, Horng J-T. Tang W-F, et al. Antimicrob Agents Chemother. 2024 Apr 3;68(4):e0095623. doi: 10.1128/aac.00956-23. Epub 2024 Mar 6. Antimicrob Agents Chemother. 2024. PMID: 38446062 Free article.
Dynamic Changes of the Blood Chemistry in Syrian Hamsters Post-Acute COVID-19.
Hsu CJ, Lin WC, Chou YC, Yang CM, Wu HL, Cheng YH, Liu PC, Chang JY, Chen HY, Sun JR. Hsu CJ, et al. Among authors: yang cm. Microbiol Spectr. 2022 Feb 23;10(1):e0236221. doi: 10.1128/spectrum.02362-21. Epub 2022 Feb 23. Microbiol Spectr. 2022. PMID: 35196799 Free PMC article.
Synthesis, evaluation, and mechanism of 1-(4-(arylethylenylcarbonyl)phenyl)-4-carboxy-2-pyrrolidinones as potent reversible SARS-CoV-2 entry inhibitors.
Palla SR, Li CW, Chao TL, Lo HV, Liu JJ, Pan MY, Chiu YT, Lin WC, Hu CW, Yang CM, Chen YY, Fang JT, Lin SW, Lin YT, Lin HC, Kuo CJ, Wang LH, Chang SY, Liang PH. Palla SR, et al. Among authors: yang cm. Antiviral Res. 2023 Nov;219:105735. doi: 10.1016/j.antiviral.2023.105735. Epub 2023 Oct 18. Antiviral Res. 2023. PMID: 37858764
1,155 results