Slassi A - Search Results

1

Recent advances in non-competitive mGlu5 receptor antagonists and their potential therapeutic applications.

Slassi A, Isaac M, Edwards L, Minidis A, Wensbo D, Mattsson J, Nilsson K, Raboisson P, McLeod D, Stormann TM, Hammerland LG, Johnson E. Slassi A, et al. Curr Top Med Chem. 2005;5(9):897-911. doi: 10.2174/1568026054750236. Curr Top Med Chem. 2005. PMID: 16178734 Review.

2

Recent advances in 5-HT1B/1D receptor antagonists and agonists and their potential therapeutic applications.

Slassi A. Slassi A. Curr Top Med Chem. 2002 Jun;2(6):559-74. doi: 10.2174/1568026023393903. Curr Top Med Chem. 2002. PMID: 12052194 Review.

3

Recent advances in 5-HT(1D)-selective agonists.

Isaac M, Slassi A. Isaac M, et al. Among authors: slassi a. IDrugs. 2001 Feb;4(2):189-96. IDrugs. 2001. PMID: 16032481 No abstract available.

4

1-(Bicyclopiperazinyl)ethylindoles and 1-(homopiperazinyl)ethyl-indoles as highly selective and potent 5-HT(7) receptor ligands.

Isaac MB, Xin T, O'Brien A, St-Martin D, Naismith A, MacLean N, Wilson J, Demchyshyn L, Tehim A, Slassi A. Isaac MB, et al. Among authors: slassi a. Bioorg Med Chem Lett. 2002 Sep 2;12(17):2451-4. doi: 10.1016/s0960-894x(02)00438-9. Bioorg Med Chem Lett. 2002. PMID: 12161155

5

Discovery and characterization of AZD9272 and AZD6538-Two novel mGluR5 negative allosteric modulators selected for clinical development.

Raboisson P, Breitholtz-Emanuelsson A, Dahllöf H, Edwards L, Heaton WL, Isaac M, Jarvie K, Kers A, Minidis AB, Nordmark A, Sheehan SM, Slassi A, Ström P, Terelius Y, Wensbo D, Wilson JM, Xin T, McLeod DA. Raboisson P, et al. Among authors: slassi a. Bioorg Med Chem Lett. 2012 Nov 15;22(22):6974-9. doi: 10.1016/j.bmcl.2012.08.100. Epub 2012 Sep 21. Bioorg Med Chem Lett. 2012. PMID: 23046966

6

Pyrrolo[3,2,1-ij]quinoline derivatives, a 5-HT2c receptor agonist with selectivity over the 5-HT2a receptor: potential therapeutic applications for epilepsy and obesity.

Isaac M, Slassi A, O'Brien A, Edwards L, MacLean N, Bueschkens D, Lee DK, McCallum K, De Lannoy I, Demchyshyn L, Kamboj R. Isaac M, et al. Among authors: slassi a. Bioorg Med Chem Lett. 2000 May 1;10(9):919-21. doi: 10.1016/s0960-894x(00)00141-4. Bioorg Med Chem Lett. 2000. PMID: 10853660

7

6-Bicyclopiperazinyl-1-arylsulfonylindoles and 6-bicyclopiperidinyl-1-arylsulfonylindoles derivatives as novel, potent, and selective 5-HT6 receptor antagonists.

Isaac M, Slassi A, Xin T, MacLean N, Wilson J, McCallum K, Wang H, Demchyshyn L. Isaac M, et al. Among authors: slassi a. Bioorg Med Chem Lett. 2000 Aug 7;10(15):1719-21. doi: 10.1016/s0960-894x(00)00320-6. Bioorg Med Chem Lett. 2000. PMID: 10937732

8

5,5-Diaryl-2-amino-4-pentenoates as novel, potent, and selective glycine transporter type-2 reuptake inhibitors.

Isaac M, Slassi A, Silva KD, Arora J, MacLean N, Hung B, McCallum K. Isaac M, et al. Among authors: slassi a. Bioorg Med Chem Lett. 2001 Jun 4;11(11):1371-3. doi: 10.1016/s0960-894x(01)00253-0. Bioorg Med Chem Lett. 2001. PMID: 11378357

9

(R)-3-(N-methylpyrrolidin-2-ylmethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity h5-HT1B/1D ligands.

Egle I, MacLean N, Demchyshyn L, Edwards L, Slassi A, Tehim A. Egle I, et al. Among authors: slassi a. Bioorg Med Chem Lett. 2003 Oct 20;13(20):3419-21. doi: 10.1016/s0960-894x(03)00779-0. Bioorg Med Chem Lett. 2003. PMID: 14505640

10

3-(2-pyrrolidin-1-ylethyl)-5-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole derivatives as high affinity human 5-HT(1B/1D) ligands.

Egle I, MacLean N, Demchyshyn L, Edwards L, Slassi A, Tehim A. Egle I, et al. Among authors: slassi a. Bioorg Med Chem Lett. 2004 Feb 9;14(3):727-9. doi: 10.1016/j.bmcl.2003.11.023. Bioorg Med Chem Lett. 2004. PMID: 14741277

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