Koh JT - Search Results

1

Link KH, Shi Y, Koh JT. Link KH, et al. Among authors: koh jt. J Am Chem Soc. 2005 Sep 28;127(38):13088-9. doi: 10.1021/ja0531226. J Am Chem Soc. 2005. PMID: 16173704 Free PMC article.

2

Functionally orthogonal ligand-receptor pairs for the selective regulation of gene expression generated by manipulation of charged residues at the ligand-receptor interface of ER alpha and ER beta.

Shi Y, Koh JT. Shi Y, et al. Among authors: koh jt. J Am Chem Soc. 2002 Jun 19;124(24):6921-8. doi: 10.1021/ja016897x. J Am Chem Soc. 2002. PMID: 12059215

3

Light-activated transcription and repression by using photocaged SERMs.

Shi Y, Koh JT. Shi Y, et al. Among authors: koh jt. Chembiochem. 2004 Jun 7;5(6):788-96. doi: 10.1002/cbic.200300823. Chembiochem. 2004. PMID: 15174161

4

Photo-caged agonists of the nuclear receptors RARgamma and TRbeta provide unique time-dependent gene expression profiles for light-activated gene patterning.

Link KH, Cruz FG, Ye HF, O'reilly KE, Dowdell S, Koh JT. Link KH, et al. Among authors: koh jt. Bioorg Med Chem. 2004 Nov 15;12(22):5949-59. doi: 10.1016/j.bmc.2004.08.022. Bioorg Med Chem. 2004. PMID: 15498671

5

Mutant-selective thyromimetics for the chemical rescue of thyroid hormone receptor mutants associated with resistance to thyroid hormone.

Shi Y, Ye H, Link KH, Putnam MC, Hubner I, Dowdell S, Koh JT. Shi Y, et al. Among authors: koh jt. Biochemistry. 2005 Mar 29;44(12):4612-26. doi: 10.1021/bi0482349. Biochemistry. 2005. PMID: 15779888

6

Selective regulation of gene expression by an orthogonal estrogen receptor-ligand pair created by polar-group exchange.

Shi Y, Koh JT. Shi Y, et al. Among authors: koh jt. Chem Biol. 2001 May;8(5):501-10. doi: 10.1016/s1074-5521(01)00028-x. Chem Biol. 2001. PMID: 11358696

7

Design and synthesis of complementing ligands for mutant thyroid hormone receptor TRbeta(R320H): a tailor-made approach toward the treatment of resistance to thyroid hormone.

Hashimoto A, Shi Y, Drake K, Koh JT. Hashimoto A, et al. Among authors: koh jt. Bioorg Med Chem. 2005 Jun 1;13(11):3627-39. doi: 10.1016/j.bmc.2005.03.040. Bioorg Med Chem. 2005. PMID: 15862991

8

Light-activated gene expression directs segregation of co-cultured cells in vitro.

Sauers DJ, Temburni MK, Biggins JB, Ceo LM, Galileo DS, Koh JT. Sauers DJ, et al. Among authors: koh jt. ACS Chem Biol. 2010 Mar 19;5(3):313-20. doi: 10.1021/cb9002305. ACS Chem Biol. 2010. PMID: 20050613

9

A functionally orthogonal ligand-receptor pair created by targeting the allosteric mechanism of the thyroid hormone receptor.

Hassan AQ, Koh JT. Hassan AQ, et al. Among authors: koh jt. J Am Chem Soc. 2006 Jul 12;128(27):8868-74. doi: 10.1021/ja060760v. J Am Chem Soc. 2006. PMID: 16819881 Free PMC article.

10

Circumventing anti-androgen resistance by molecular design.

McGinley PL, Koh JT. McGinley PL, et al. Among authors: koh jt. J Am Chem Soc. 2007 Apr 4;129(13):3822-3. doi: 10.1021/ja0701154. Epub 2007 Mar 10. J Am Chem Soc. 2007. PMID: 17348658 Free PMC article.

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