Georgiades SN - Search Results

1

Total synthesis of psammaplysenes A and B, naturally occurring inhibitors of FOXO1a nuclear export.

Georgiades SN, Clardy J. Georgiades SN, et al. Org Lett. 2005 Sep 15;7(19):4091-4. doi: 10.1021/ol0513286. Org Lett. 2005. PMID: 16146359

2

Preparation of a psammaplysene-based library.

Georgiades SN, Clardy J. Georgiades SN, et al. Org Lett. 2006 Sep 14;8(19):4251-4. doi: 10.1021/ol061599w. Org Lett. 2006. PMID: 16956199 Free PMC article.

3

Synthetic libraries of tyrosine-derived bacterial metabolites.

Georgiades SN, Clardy J. Georgiades SN, et al. Bioorg Med Chem Lett. 2008 May 15;18(10):3117-21. doi: 10.1016/j.bmcl.2007.10.058. Epub 2007 Oct 22. Bioorg Med Chem Lett. 2008. PMID: 17983747 Free PMC article.

4

FOXO3a is broadly neuroprotective in vitro and in vivo against insults implicated in motor neuron diseases.

Mojsilovic-Petrovic J, Nedelsky N, Boccitto M, Mano I, Georgiades SN, Zhou W, Liu Y, Neve RL, Taylor JP, Driscoll M, Clardy J, Merry D, Kalb RG. Mojsilovic-Petrovic J, et al. Among authors: georgiades sn. J Neurosci. 2009 Jun 24;29(25):8236-47. doi: 10.1523/JNEUROSCI.1805-09.2009. J Neurosci. 2009. PMID: 19553463 Free PMC article.

5

A small molecule mimicking a phosphatidylinositol (4,5)-bisphosphate binding pleckstrin homology domain.

Mak LH, Georgiades SN, Rosivatz E, Whyte GF, Mirabelli M, Vilar R, Woscholski R. Mak LH, et al. Among authors: georgiades sn. ACS Chem Biol. 2011 Dec 16;6(12):1382-90. doi: 10.1021/cb2003187. Epub 2011 Oct 10. ACS Chem Biol. 2011. PMID: 21958214 Free article.

6

Identification of a potent activator of Akt phosphorylation from a novel series of phenolic, picolinic, pyridino, and hydroxamic zinc(II) complexes.

Georgiades SN, Mak LH, Angurell I, Rosivatz E, Firouz Mohd Mustapa M, Polychroni C, Woscholski R, Vilar R. Georgiades SN, et al. J Biol Inorg Chem. 2011 Feb;16(2):195-208. doi: 10.1007/s00775-010-0716-0. Epub 2010 Oct 23. J Biol Inorg Chem. 2011. PMID: 20972690 Free article.

7

Interaction of metal complexes with G-quadruplex DNA.

Georgiades SN, Abd Karim NH, Suntharalingam K, Vilar R. Georgiades SN, et al. Angew Chem Int Ed Engl. 2010 Jun 1;49(24):4020-34. doi: 10.1002/anie.200906363. Angew Chem Int Ed Engl. 2010. PMID: 20503216 Review.

8

Recent Developments in Small-Molecule Ligands of Medicinal Relevance for Harnessing the Anticancer Potential of G-Quadruplexes.

Savva L, Georgiades SN. Savva L, et al. Among authors: georgiades sn. Molecules. 2021 Feb 5;26(4):841. doi: 10.3390/molecules26040841. Molecules. 2021. PMID: 33562720 Free PMC article. Review.

9

Inhibition of mitogen-activated protein kinase (MAPK) and cyclin-dependent kinase 2 (Cdk2) by platinum(II) phenanthroline complexes.

Child ES, Georgiades SN, Rose KN, Stafford VS, Patel CB, Steinke JH, Mann DJ, Vilar R. Child ES, et al. Among authors: georgiades sn. J Chem Biol. 2011 Oct;4(4):159-65. doi: 10.1007/s12154-011-0059-5. Epub 2011 Feb 26. J Chem Biol. 2011. PMID: 22368708 Free PMC article.

10

Gaining Insights on the Interactions of a Class of Decorated (2-([2,2'-Bipyridin]-6-yl)phenyl)platinum Compounds with c-Myc Oncogene Promoter G-Quadruplex and Other DNA Structures.

Savva L, Fossépré M, Keramidas O, Themistokleous A, Rizeq N, Panagiotou N, Leclercq M, Nicolaidou E, Surin M, Hayes SC, Georgiades SN. Savva L, et al. Among authors: georgiades sn. Chemistry. 2022 Sep 27;28(54):e202201497. doi: 10.1002/chem.202201497. Epub 2022 Aug 1. Chemistry. 2022. PMID: 35726630 Free PMC article.

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