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Mutations in both env and gag genes are required for HIV-1 resistance to the polysulfonic dendrimer SPL2923, as corroborated by chimeric virus technology.
Hantson A, Fikkert V, Van Remoortel B, Pannecouque C, Cherepanov P, Matthews B, Holan G, De Clercq E, Vandamme AM, Debyser Z, Witvrouw M. Hantson A, et al. Among authors: witvrouw m. Antivir Chem Chemother. 2005;16(4):253-66. doi: 10.1177/095632020501600405. Antivir Chem Chemother. 2005. PMID: 16130523 Free article.
In search of authentic inhibitors of HIV-1 integration.
Debyser Z, Cherepanov P, Van Maele B, De Clercq E, Witvrouw M. Debyser Z, et al. Among authors: witvrouw m. Antivir Chem Chemother. 2002 Jan;13(1):1-15. doi: 10.1177/095632020201300101. Antivir Chem Chemother. 2002. PMID: 12180645 Free article. Review.
Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations.
Fikkert V, Van Maele B, Vercammen J, Hantson A, Van Remoortel B, Michiels M, Gurnari C, Pannecouque C, De Maeyer M, Engelborghs Y, De Clercq E, Debyser Z, Witvrouw M. Fikkert V, et al. Among authors: witvrouw m. J Virol. 2003 Nov;77(21):11459-70. doi: 10.1128/jvi.77.21.11459-11470.2003. J Virol. 2003. PMID: 14557631 Free PMC article.
Gabryelski, W. Schleif, C. Blau, and M. D. Miller, Science 287:646-650, 2000). We have now studied the development of antiviral resistance to L-708,906 by growing HIV-1 strains in the presence of increasing concentrations of the compound. ...Pluymers, B. Van Maele, V. Tetz …
Gabryelski, W. Schleif, C. Blau, and M. D. Miller, Science 287:646-650, 2000). We have now studied the development of antiviral resis …
Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137.
Hombrouck A, Voet A, Van Remoortel B, Desadeleer C, De Maeyer M, Debyser Z, Witvrouw M. Hombrouck A, et al. Among authors: witvrouw m. Antimicrob Agents Chemother. 2008 Jun;52(6):2069-78. doi: 10.1128/AAC.00911-07. Epub 2008 Mar 31. Antimicrob Agents Chemother. 2008. PMID: 18378713 Free PMC article.
Inhibition of human immunodeficiency virus type 1 integration by diketo derivatives.
Pluymers W, Pais G, Van Maele B, Pannecouque C, Fikkert V, Burke TR Jr, De Clercq E, Witvrouw M, Neamati N, Debyser Z. Pluymers W, et al. Among authors: witvrouw m. Antimicrob Agents Chemother. 2002 Oct;46(10):3292-7. doi: 10.1128/AAC.46.10.3292-3297.2002. Antimicrob Agents Chemother. 2002. PMID: 12234864 Free PMC article.
152 results