Hofstra RM - Search Results

1

Determination of TP53 mutation is more relevant than microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients.

Westra JL, Schaapveld M, Hollema H, de Boer JP, Kraak MM, de Jong D, ter Elst A, Mulder NH, Buys CH, Hofstra RM, Plukker JT. Westra JL, et al. Among authors: hofstra rm. J Clin Oncol. 2005 Aug 20;23(24):5635-43. doi: 10.1200/JCO.2005.04.096. J Clin Oncol. 2005. PMID: 16110022 Clinical Trial.

2

Toward new strategies to select young endometrial cancer patients for mismatch repair gene mutation analysis.

Berends MJ, Wu Y, Sijmons RH, van der Sluis T, Ek WB, Ligtenberg MJ, Arts NJ, ten Hoor KA, Kleibeuker JH, de Vries EG, Mourits MJ, Hollema H, Buys CH, Hofstra RM, van der Zee AG. Berends MJ, et al. Among authors: hofstra rm. J Clin Oncol. 2003 Dec 1;21(23):4364-70. doi: 10.1200/JCO.2003.04.094. J Clin Oncol. 2003. PMID: 14645426

3

A substantial proportion of microsatellite-unstable colon tumors carry TP53 mutations while not showing chromosomal instability.

Westra JL, Boven LG, van der Vlies P, Faber H, Sikkema B, Schaapveld M, Dijkhuizen T, Hollema H, Buys CH, Plukker JT, Kok K, Hofstra RM. Westra JL, et al. Among authors: hofstra rm. Genes Chromosomes Cancer. 2005 Jun;43(2):194-201. doi: 10.1002/gcc.20148. Genes Chromosomes Cancer. 2005. PMID: 15729700

4

Prognostic significance of K-ras and TP53 mutations in the role of adjuvant chemotherapy on survival in patients with Dukes C colon cancer.

Bleeker WA, Hayes VM, Karrenbeld A, Hofstra RM, Verlind E, Hermans J, Poppema S, Buys CH, Plukker JT. Bleeker WA, et al. Among authors: hofstra rm. Dis Colon Rectum. 2001 Mar;44(3):358-63. doi: 10.1007/BF02234733. Dis Colon Rectum. 2001. PMID: 11289281

5

Genetic alterations in locally advanced stage II/III colon cancer: a search for prognostic markers.

Westra JL, Plukker JT, Buys CH, Hofstra RM. Westra JL, et al. Among authors: hofstra rm. Clin Colorectal Cancer. 2004 Nov;4(4):252-9. doi: 10.3816/ccc.2004.n.024. Clin Colorectal Cancer. 2004. PMID: 15555207 Review.

6

Predictive value of thymidylate synthase and dihydropyrimidine dehydrogenase protein expression on survival in adjuvantly treated stage III colon cancer patients.

Westra JL, Hollema H, Schaapveld M, Platteel I, Oien KA, Keith WN, Mauritz R, Peters GJ, Buys CH, Hofstra RM, Plukker JT. Westra JL, et al. Among authors: hofstra rm. Ann Oncol. 2005 Oct;16(10):1646-53. doi: 10.1093/annonc/mdi316. Epub 2005 Jul 12. Ann Oncol. 2005. PMID: 16012177 Free article.

7

Molecular and clinical characteristics of MSH6 variants: an analysis of 25 index carriers of a germline variant.

Berends MJ, Wu Y, Sijmons RH, Mensink RG, van der Sluis T, Hordijk-Hos JM, de Vries EG, Hollema H, Karrenbeld A, Buys CH, van der Zee AG, Hofstra RM, Kleibeuker JH. Berends MJ, et al. Among authors: hofstra rm. Am J Hum Genet. 2002 Jan;70(1):26-37. doi: 10.1086/337944. Am J Hum Genet. 2002. PMID: 11709755 Free PMC article.

8

Do microsatellite instability profiles really differ between colorectal and endometrial tumors?

Ferreira AM, Westers H, Wu Y, Niessen RC, Olderode-Berends M, van der Sluis T, van der Zee AG, Hollema H, Kleibeuker JH, Sijmons RH, Hofstra RM. Ferreira AM, et al. Among authors: hofstra rm. Genes Chromosomes Cancer. 2009 Jul;48(7):552-7. doi: 10.1002/gcc.20664. Genes Chromosomes Cancer. 2009. PMID: 19373783

9

Comprehensive TP53-denaturing gradient gel electrophoresis mutation detection assay also applicable to archival paraffin-embedded tissue.

Hayes VM, Bleeker W, Verlind E, Timmer T, Karrenbeld A, Plukker JT, Marx MP, Hofstra RM, Buys CH. Hayes VM, et al. Among authors: hofstra rm. Diagn Mol Pathol. 1999 Mar;8(1):2-10. doi: 10.1097/00019606-199903000-00002. Diagn Mol Pathol. 1999. PMID: 10408787

10

Association of hereditary nonpolyposis colorectal cancer-related tumors displaying low microsatellite instability with MSH6 germline mutations.

Wu Y, Berends MJ, Mensink RG, Kempinga C, Sijmons RH, van Der Zee AG, Hollema H, Kleibeuker JH, Buys CH, Hofstra RM. Wu Y, et al. Among authors: hofstra rm. Am J Hum Genet. 1999 Nov;65(5):1291-8. doi: 10.1086/302612. Am J Hum Genet. 1999. PMID: 10521294 Free PMC article.

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