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beta-amyloid is different in normal aging and in Alzheimer disease.
Piccini A, Russo C, Gliozzi A, Relini A, Vitali A, Borghi R, Giliberto L, Armirotti A, D'Arrigo C, Bachi A, Cattaneo A, Canale C, Torrassa S, Saido TC, Markesbery W, Gambetti P, Tabaton M. Piccini A, et al. Among authors: saido tc. J Biol Chem. 2005 Oct 7;280(40):34186-92. doi: 10.1074/jbc.M501694200. Epub 2005 Aug 15. J Biol Chem. 2005. PMID: 16103127 Free article.
Molecular dissection of domains in mutant presenilin 2 that mediate overproduction of amyloidogenic forms of amyloid beta peptides. Inability of truncated forms of PS2 with familial Alzheimer's disease mutation to increase secretion of Abeta42.
Tomita T, Tokuhiro S, Hashimoto T, Aiba K, Saido TC, Maruyama K, Iwatsubo T. Tomita T, et al. Among authors: saido tc. J Biol Chem. 1998 Aug 14;273(33):21153-60. doi: 10.1074/jbc.273.33.21153. J Biol Chem. 1998. PMID: 9694871 Free article.
Presenilin-1 mutations in Alzheimer's disease.
Russo C, Schettini G, Saido TC, Hulette C, Lippa C, Lannfelt L, Ghetti B, Gambetti P, Tabaton M, Teller JK. Russo C, et al. Among authors: saido tc. Nature. 2000 Jun 1;405(6786):531-2. doi: 10.1038/35014735. Nature. 2000. PMID: 10850703 No abstract available.
Neprilysin degrades both amyloid beta peptides 1-40 and 1-42 most rapidly and efficiently among thiorphan- and phosphoramidon-sensitive endopeptidases.
Shirotani K, Tsubuki S, Iwata N, Takaki Y, Harigaya W, Maruyama K, Kiryu-Seo S, Kiyama H, Iwata H, Tomita T, Iwatsubo T, Saido TC. Shirotani K, et al. Among authors: saido tc. J Biol Chem. 2001 Jun 15;276(24):21895-901. doi: 10.1074/jbc.M008511200. Epub 2001 Mar 6. J Biol Chem. 2001. PMID: 11278416 Free article.
487 results