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Molecular mechanisms of sweet receptor function.
Jiang P, Cui M, Ji Q, Snyder L, Liu Z, Benard L, Margolskee RF, Osman R, Max M. Jiang P, et al. Among authors: osman r. Chem Senses. 2005 Jan;30 Suppl 1:i17-8. doi: 10.1093/chemse/bjh091. Chem Senses. 2005. PMID: 15738096 No abstract available.
A model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Evidence for a second direct interaction between transmembrane helix 3 and TRH.
Perlman JH, Laakkonen L, Osman R, Gershengorn MC. Perlman JH, et al. Among authors: osman r. J Biol Chem. 1994 Sep 23;269(38):23383-6. J Biol Chem. 1994. PMID: 8089099 Free article.
We showed that tyrosine at position 106 in transmembrane helix 3 of the TRH receptor directly binds the ring carbonyl of the pyroglutamyl moiety of TRH (Perlman, J. H., Thaw, C. N., Laakkonen L., Bowers, C. Y., Osman, R., and Gershengorn, M. C. (1994) J. Biol. Chem. …
We showed that tyrosine at position 106 in transmembrane helix 3 of the TRH receptor directly binds the ring carbonyl of the pyroglutamyl mo …
Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor.
Perlman JH, Colson AO, Wang W, Bence K, Osman R, Gershengorn MC. Perlman JH, et al. Among authors: osman r. J Biol Chem. 1997 May 2;272(18):11937-42. doi: 10.1074/jbc.272.18.11937. J Biol Chem. 1997. PMID: 9115256 Free article.
A computer-generated model of the thyrotropin-releasing hormone receptor (TRH-R) indicated that conserved Asp-71 (TM-2) could interact with conserved asparagines 316 (TM-7) and 43 (TM-1). ...The maximal activities of N43A and N316A TRH-Rs were diminished, whereas D71A (Per …
A computer-generated model of the thyrotropin-releasing hormone receptor (TRH-R) indicated that conserved Asp-71 (TM-2) could interac …
354 results