Koning GA - Search Results

1

Coformulated N-octanoyl-glucosylceramide improves cellular delivery and cytotoxicity of liposomal doxorubicin.

Veldman RJ, Koning GA, van Hell A, Zerp S, Vink SR, Storm G, Verheij M, van Blitterswijk WJ. Veldman RJ, et al. Among authors: koning ga. J Pharmacol Exp Ther. 2005 Nov;315(2):704-10. doi: 10.1124/jpet.105.087486. Epub 2005 Jul 22. J Pharmacol Exp Ther. 2005. PMID: 16040815

2

Enriching lipid nanovesicles with short-chain glucosylceramide improves doxorubicin delivery and efficacy in solid tumors.

van Lummel M, van Blitterswijk WJ, Vink SR, Veldman RJ, van der Valk MA, Schipper D, Dicheva BM, Eggermont AM, ten Hagen TL, Verheij M, Koning GA. van Lummel M, et al. Among authors: koning ga. FASEB J. 2011 Jan;25(1):280-9. doi: 10.1096/fj.10-163709. Epub 2010 Sep 27. FASEB J. 2011. PMID: 20876209

3

Targeted drug delivery systems for the intracellular delivery of macromolecular drugs.

Koning GA, Storm G. Koning GA, et al. Drug Discov Today. 2003 Jun 1;8(11):482-3. doi: 10.1016/s1359-6446(03)02699-0. Drug Discov Today. 2003. PMID: 12818515 No abstract available.

4

Improving intracellular doxorubicin delivery through nanoliposomes equipped with selective tumor cell membrane permeabilizing short-chain sphingolipids.

Pedrosa LR, van Hell A, Süss R, van Blitterswijk WJ, Seynhaeve AL, van Cappellen WA, Eggermont AM, ten Hagen TL, Verheij M, Koning GA. Pedrosa LR, et al. Among authors: koning ga. Pharm Res. 2013 Jul;30(7):1883-95. doi: 10.1007/s11095-013-1031-6. Epub 2013 May 11. Pharm Res. 2013. PMID: 23666266

5

Defined lipid analogues induce transient channels to facilitate drug-membrane traversal and circumvent cancer therapy resistance.

van Hell AJ, Melo MN, van Blitterswijk WJ, Gueth DM, Braumuller TM, Pedrosa LR, Song JY, Marrink SJ, Koning GA, Jonkers J, Verheij M. van Hell AJ, et al. Among authors: koning ga. Sci Rep. 2013;3:1949. doi: 10.1038/srep01949. Sci Rep. 2013. PMID: 23739489 Free PMC article.

6

Anti-tumor efficacy of tumor vasculature-targeted liposomal doxorubicin.

Schiffelers RM, Koning GA, ten Hagen TL, Fens MH, Schraa AJ, Janssen AP, Kok RJ, Molema G, Storm G. Schiffelers RM, et al. Among authors: koning ga. J Control Release. 2003 Aug 28;91(1-2):115-22. doi: 10.1016/s0168-3659(03)00240-2. J Control Release. 2003. PMID: 12932643

7

Strategies for cytosolic delivery of liposomal macromolecules.

Fretz MM, Mastrobattista E, Koning GA, Jiskoot W, Storm G. Fretz MM, et al. Among authors: koning ga. Int J Pharm. 2005 Jul 25;298(2):305-9. doi: 10.1016/j.ijpharm.2005.02.040. Int J Pharm. 2005. PMID: 15941633 Review.

8

Short-chain glycoceramides promote intracellular mitoxantrone delivery from novel nanoliposomes into breast cancer cells.

Pedrosa LR, Ten Hagen TL, Süss R, van Hell A, Eggermont AM, Verheij M, Koning GA. Pedrosa LR, et al. Among authors: koning ga. Pharm Res. 2015 Apr;32(4):1354-67. doi: 10.1007/s11095-014-1539-4. Epub 2014 Oct 16. Pharm Res. 2015. PMID: 25319103

9

C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake.

Cordeiro Pedrosa LR, van Cappellen WA, Steurer B, Ciceri D, ten Hagen TL, Eggermont AM, Verheij M, Goñi FM, Koning GA, Contreras FX. Cordeiro Pedrosa LR, et al. Among authors: koning ga. Biochim Biophys Acta. 2015 Aug;1848(8):1656-70. doi: 10.1016/j.bbamem.2015.04.011. Epub 2015 Apr 24. Biochim Biophys Acta. 2015. PMID: 25917957 Free article.

10

Plasma membrane targeting by short chain sphingolipids inserted in liposomes improves anti-tumor activity of mitoxantrone in an orthotopic breast carcinoma xenograft model.

Cordeiro Pedrosa LR, van Tellingen O, Soullié T, Seynhaeve AL, Eggermont AM, Ten Hagen TL, Verheij M, Koning GA. Cordeiro Pedrosa LR, et al. Among authors: koning ga. Eur J Pharm Biopharm. 2015 Aug;94:207-19. doi: 10.1016/j.ejpb.2015.05.003. Epub 2015 May 14. Eur J Pharm Biopharm. 2015. PMID: 25982691

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