De Smedt M - Search Results

1

Different thresholds of Notch signaling bias human precursor cells toward B-, NK-, monocytic/dendritic-, or T-cell lineage in thymus microenvironment.

De Smedt M, Hoebeke I, Reynvoet K, Leclercq G, Plum J. De Smedt M, et al. Blood. 2005 Nov 15;106(10):3498-506. doi: 10.1182/blood-2005-02-0496. Epub 2005 Jul 19. Blood. 2005. PMID: 16030192 Free article.

2

HOX-A10 regulates hematopoietic lineage commitment: evidence for a monocyte-specific transcription factor.

Taghon T, Stolz F, De Smedt M, Cnockaert M, Verhasselt B, Plum J, Leclercq G. Taghon T, et al. Among authors: de smedt m. Blood. 2002 Feb 15;99(4):1197-204. doi: 10.1182/blood.v99.4.1197. Blood. 2002. PMID: 11830466 Free article.

3

Adapted NOD/SCID model supports development of phenotypically and functionally mature T cells from human umbilical cord blood CD34(+) cells.

Kerre TC, De Smet G, De Smedt M, Zippelius A, Pittet MJ, Langerak AW, De Bosscher J, Offner F, Vandekerckhove B, Plum J. Kerre TC, et al. Among authors: de smet g, de smedt m, de bosscher j. Blood. 2002 Mar 1;99(5):1620-6. doi: 10.1182/blood.v99.5.1620. Blood. 2002. PMID: 11861276 Free article.

4

Active form of Notch imposes T cell fate in human progenitor cells.

De Smedt M, Reynvoet K, Kerre T, Taghon T, Verhasselt B, Vandekerckhove B, Leclercq G, Plum J. De Smedt M, et al. J Immunol. 2002 Sep 15;169(6):3021-9. doi: 10.4049/jimmunol.169.6.3021. J Immunol. 2002. PMID: 12218117

5

Human bone marrow CD34+ progenitor cells mature to T cells on OP9-DL1 stromal cell line without thymus microenvironment.

De Smedt M, Hoebeke I, Plum J. De Smedt M, et al. Blood Cells Mol Dis. 2004 Nov-Dec;33(3):227-32. doi: 10.1016/j.bcmd.2004.08.007. Blood Cells Mol Dis. 2004. PMID: 15528136

6

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells.

Hoebeke I, De Smedt M, Van de Walle I, Reynvoet K, De Smet G, Plum J, Leclercq G. Hoebeke I, et al. Among authors: de smedt m, de smet g. Blood. 2006 Apr 1;107(7):2879-81. doi: 10.1182/blood-2005-05-1815. Epub 2005 Dec 1. Blood. 2006. PMID: 16322473 Free article.

7

Notch signaling induces cytoplasmic CD3 epsilon expression in human differentiating NK cells.

De Smedt M, Taghon T, Van de Walle I, De Smet G, Leclercq G, Plum J. De Smedt M, et al. Among authors: de smet g. Blood. 2007 Oct 1;110(7):2696-703. doi: 10.1182/blood-2007-03-082206. Epub 2007 Jul 13. Blood. 2007. PMID: 17630354 Free article.

8

Notch signaling is required for proliferation but not for differentiation at a well-defined beta-selection checkpoint during human T-cell development.

Taghon T, Van de Walle I, De Smet G, De Smedt M, Leclercq G, Vandekerckhove B, Plum J. Taghon T, et al. Among authors: de smet g, de smedt m. Blood. 2009 Apr 2;113(14):3254-63. doi: 10.1182/blood-2008-07-168906. Epub 2008 Oct 23. Blood. 2009. PMID: 18948571 Free article.

9

An early decrease in Notch activation is required for human TCR-alphabeta lineage differentiation at the expense of TCR-gammadelta T cells.

Van de Walle I, De Smet G, De Smedt M, Vandekerckhove B, Leclercq G, Plum J, Taghon T. Van de Walle I, et al. Among authors: de smet g, de smedt m. Blood. 2009 Mar 26;113(13):2988-98. doi: 10.1182/blood-2008-06-164871. Epub 2008 Dec 3. Blood. 2009. PMID: 19056690 Free article.

10

Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.

Van de Walle I, De Smet G, Gärtner M, De Smedt M, Waegemans E, Vandekerckhove B, Leclercq G, Plum J, Aster JC, Bernstein ID, Guidos CJ, Kyewski B, Taghon T. Van de Walle I, et al. Among authors: de smedt m. Blood. 2011 Apr 28;117(17):4449-59. doi: 10.1182/blood-2010-06-290049. Epub 2011 Mar 3. Blood. 2011. PMID: 21372153 Free PMC article.

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