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Page 1
Pacemaker activity and ionic currents in mouse atrioventricular node cells.
Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME. Marger L, et al. Channels (Austin). 2011 May-Jun;5(3):241-50. doi: 10.4161/chan.5.3.15264. Epub 2011 May 1. Channels (Austin). 2011. PMID: 21406959 Free PMC article.
Functional roles of Ca(v)1.3, Ca(v)3.1 and HCN channels in automaticity of mouse atrioventricular cells: insights into the atrioventricular pacemaker mechanism.
Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME. Marger L, et al. Channels (Austin). 2011 May-Jun;5(3):251-61. doi: 10.4161/chan.5.3.15266. Epub 2011 May 1. Channels (Austin). 2011. PMID: 21406960 Free PMC article.
The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation.
Mesirca P, Marger L, Toyoda F, Rizzetto R, Audoubert M, Dubel S, Torrente AG, Difrancesco ML, Muller JC, Leoni AL, Couette B, Nargeot J, Clapham DE, Wickman K, Mangoni ME. Mesirca P, et al. Among authors: marger l. J Gen Physiol. 2013 Aug;142(2):113-26. doi: 10.1085/jgp.201310996. Epub 2013 Jul 15. J Gen Physiol. 2013. PMID: 23858001 Free PMC article.
Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation.
Mesirca P, Alig J, Torrente AG, Müller JC, Marger L, Rollin A, Marquilly C, Vincent A, Dubel S, Bidaud I, Fernandez A, Seniuk A, Engeland B, Singh J, Miquerol L, Ehmke H, Eschenhagen T, Nargeot J, Wickman K, Isbrandt D, Mangoni ME. Mesirca P, et al. Among authors: marger l. Nat Commun. 2014 Aug 21;5:4664. doi: 10.1038/ncomms5664. Nat Commun. 2014. PMID: 25144323 Free PMC article.
G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block.
Mesirca P, Bidaud I, Briec F, Evain S, Torrente AG, Le Quang K, Leoni AL, Baudot M, Marger L, Chung You Chong A, Nargeot J, Striessnig J, Wickman K, Charpentier F, Mangoni ME. Mesirca P, et al. Among authors: marger l. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):E932-41. doi: 10.1073/pnas.1517181113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831068 Free PMC article.
Control of heart rate by cAMP sensitivity of HCN channels.
Alig J, Marger L, Mesirca P, Ehmke H, Mangoni ME, Isbrandt D. Alig J, et al. Among authors: marger l. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12189-94. doi: 10.1073/pnas.0810332106. Epub 2009 Jul 1. Proc Natl Acad Sci U S A. 2009. PMID: 19570998 Free PMC article.
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