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Gpcpd1-GPC metabolic pathway is dysfunctional in aging and its deficiency severely perturbs glucose metabolism.
Cikes D, Leutner M, Cronin SJF, Novatchkova M, Pfleger L, Klepochová R, Lair B, Lac M, Bergoglio C, Viguerie N, Dürnberger G, Roitinger E, Grivej M, Rullman E, Gustafsson T, Hagelkruys A, Tavernier G, Bourlier V, Knauf C, Krebs M, Kautzky-Willer A, Moro C, Krssak M, Orthofer M, Penninger JM. Cikes D, et al. Among authors: pfleger l. Nat Aging. 2024 Jan;4(1):80-94. doi: 10.1038/s43587-023-00551-6. Epub 2024 Jan 18. Nat Aging. 2024. PMID: 38238601
Increased GH/IGF-I Axis Activity Relates to Lower Hepatic Lipids and Phosphor Metabolism.
Fellinger P, Beiglböck H, Semmler G, Pfleger L, Smajis S, Baumgartner C, Gajdosik M, Marculescu R, Vila G, Winhofer Y, Scherer T, Trauner M, Kautzky-Willer A, Krssak M, Krebs M, Wolf P. Fellinger P, et al. Among authors: pfleger l. J Clin Endocrinol Metab. 2023 Sep 18;108(10):e989-e997. doi: 10.1210/clinem/dgad206. J Clin Endocrinol Metab. 2023. PMID: 37104943 Free PMC article.
Potential role of skeletal muscle glycerophosphocholine in response to altered fluid balance in humans: an in vivo nuclear magnetic resonance study.
Baumgartner C, Wolf P, Beiglböck H, Pfleger L, Fellinger P, Heitzinger G, Metz M, Leutner M, Kautzky-Willer A, Krššák M, Krebs M. Baumgartner C, et al. Among authors: pfleger l. Am J Physiol Endocrinol Metab. 2023 Apr 1;324(4):E339-E346. doi: 10.1152/ajpendo.00286.2022. Epub 2023 Feb 15. Am J Physiol Endocrinol Metab. 2023. PMID: 36791322 Free article.
Leptin increases hepatic triglyceride export via a vagal mechanism in humans.
Metz M, Beghini M, Wolf P, Pfleger L, Hackl M, Bastian M, Freudenthaler A, Harreiter J, Zeyda M, Baumgartner-Parzer S, Marculescu R, Marella N, Hannich JT, Györi G, Berlakovich G, Roden M, Krebs M, Risti R, Lõokene A, Trauner M, Kautzky-Willer A, Krššák M, Stangl H, Fürnsinn C, Scherer T. Metz M, et al. Among authors: pfleger l. Cell Metab. 2022 Nov 1;34(11):1719-1731.e5. doi: 10.1016/j.cmet.2022.09.020. Epub 2022 Oct 10. Cell Metab. 2022. PMID: 36220067 Free article. Clinical Trial.
Gluconeogenesis, But Not Glycogenolysis, Contributes to the Increase in Endogenous Glucose Production by SGLT-2 Inhibition.
Wolf P, Fellinger P, Pfleger L, Beiglböck H, Krumpolec P, Barbieri C, Gastaldelli A, Harreiter J, Metz M, Scherer T, Zeyda M, Baumgartner-Parzer S, Marculescu R, Trattnig S, Kautzky-Willer A, Krššák M, Krebs M. Wolf P, et al. Among authors: pfleger l. Diabetes Care. 2021 Feb;44(2):541-548. doi: 10.2337/dc20-1983. Epub 2020 Dec 14. Diabetes Care. 2021. PMID: 33318126
In Vivo 1 H MR Spectroscopy of Biliary Components of Human Gallbladder at 7T.
Gajdošík M, Chmelík M, Halilbasic E, Pfleger L, Klepochová R, Trauner M, Trattnig S, Krššák M. Gajdošík M, et al. Among authors: pfleger l. J Magn Reson Imaging. 2021 Jan;53(1):98-107. doi: 10.1002/jmri.27207. Epub 2020 Jun 5. J Magn Reson Imaging. 2021. PMID: 32501627 Free PMC article.
Increased ATP synthesis might counteract hepatic lipid accumulation in acromegaly.
Fellinger P, Wolf P, Pfleger L, Krumpolec P, Krssak M, Klavins K, Wolfsberger S, Micko A, Carey P, Gürtl B, Vila G, Raber W, Fürnsinn C, Scherer T, Trattnig S, Kautzky-Willer A, Krebs M, Winhofer Y. Fellinger P, et al. Among authors: pfleger l. JCI Insight. 2020 Mar 12;5(5):e134638. doi: 10.1172/jci.insight.134638. JCI Insight. 2020. PMID: 32106111 Free PMC article.
53 results