Gudmundsson OS - Search Results

1

A novel hPepT1 stably transfected cell line: establishing a correlation between expression and function.

Herrera-Ruiz D, Faria TN, Bhardwaj RK, Timoszyk J, Gudmundsson OS, Moench P, Wall DA, Smith RL, Knipp GT. Herrera-Ruiz D, et al. Among authors: gudmundsson os. Mol Pharm. 2004 Mar-Apr;1(2):136-44. doi: 10.1021/mp034011l. Mol Pharm. 2004. PMID: 15832510

2

Delineation of human peptide transporter 1 (hPepT1)-mediated uptake and transport of substrates with varying transporter affinities utilizing stably transfected hPepT1/Madin-Darby canine kidney clones and Caco-2 cells.

Bhardwaj RK, Herrera-Ruiz D, Sinko PJ, Gudmundsson OS, Knipp G. Bhardwaj RK, et al. Among authors: gudmundsson os. J Pharmacol Exp Ther. 2005 Sep;314(3):1093-100. doi: 10.1124/jpet.105.087148. Epub 2005 May 18. J Pharmacol Exp Ther. 2005. PMID: 15901802

3

Expression of multiple drug resistance conferring proteins in normal Chinese and Caucasian small and large intestinal tissue samples.

Wang Q, Bhardwaj RK, Herrera-Ruiz D, Hanna NN, Hanna IT, Gudmundsson OS, Buranachokpaisan T, Hidalgo IJ, Knipp GT. Wang Q, et al. Among authors: gudmundsson os. Mol Pharm. 2004 Nov-Dec;1(6):447-54. doi: 10.1021/mp049942r. Mol Pharm. 2004. PMID: 16028356

4

Spatial expression patterns of peptide transporters in the human and rat gastrointestinal tracts, Caco-2 in vitro cell culture model, and multiple human tissues.

Herrera-Ruiz D, Wang Q, Gudmundsson OS, Cook TJ, Smith RL, Faria TN, Knipp GT. Herrera-Ruiz D, et al. Among authors: gudmundsson os. AAPS PharmSci. 2001;3(1):E9. doi: 10.1208/ps030109. AAPS PharmSci. 2001. PMID: 11741260 Free PMC article.

5

A computational model for the prediction of aqueous solubility that includes crystal packing, intrinsic solubility, and ionization effects.

Johnson SR, Chen XQ, Murphy D, Gudmundsson O. Johnson SR, et al. Mol Pharm. 2007 Jul-Aug;4(4):513-23. doi: 10.1021/mp070030+. Epub 2007 Jun 1. Mol Pharm. 2007. PMID: 17539661

6

Discovery pharmaceutics--challenges and opportunities.

Chen XQ, Antman MD, Gesenberg C, Gudmundsson OS. Chen XQ, et al. Among authors: gudmundsson os. AAPS J. 2006 Jun 2;8(2):E402-8. doi: 10.1007/BF02854912. AAPS J. 2006. PMID: 16796392 Free PMC article.

7

Lipophilic salts of poorly soluble compounds to enable high-dose lipidic SEDDS formulations in drug discovery.

Morgen M, Saxena A, Chen XQ, Miller W, Nkansah R, Goodwin A, Cape J, Haskell R, Su C, Gudmundsson O, Hageman M, Kumar A, Chowan GS, Rao A, Holenarsipur VK. Morgen M, et al. Eur J Pharm Biopharm. 2017 Aug;117:212-223. doi: 10.1016/j.ejpb.2017.04.021. Epub 2017 Apr 21. Eur J Pharm Biopharm. 2017. PMID: 28438550 Free article.

8

Application of lipid-based formulations in drug discovery.

Chen XQ, Gudmundsson OS, Hageman MJ. Chen XQ, et al. Among authors: gudmundsson os. J Med Chem. 2012 Sep 27;55(18):7945-56. doi: 10.1021/jm3006433. Epub 2012 Aug 17. J Med Chem. 2012. PMID: 22779739 Review. No abstract available.

9

Oral delivery of highly lipophilic poorly water-soluble drugs: spray-dried dispersions to improve oral absorption and enable high-dose toxicology studies of a P2Y1 antagonist.

Chen XQ, Stefanski K, Shen H, Huang C, Caporuscio C, Yang W, Lam P, Su C, Gudmundsson O, Hageman M. Chen XQ, et al. J Pharm Sci. 2014 Dec;103(12):3924-3931. doi: 10.1002/jps.24199. Epub 2014 Oct 10. J Pharm Sci. 2014. PMID: 25308627

10

Oral Delivery of Highly Lipophilic, Poorly Water-Soluble Drugs: Self-Emulsifying Drug Delivery Systems to Improve Oral Absorption and Enable High-Dose Toxicology Studies of a Cholesteryl Ester Transfer Protein Inhibitor in Preclinical Species.

Chen XQ, Ziemba T, Huang C, Chang M, Xu C, Qiao JX, Wang TC, Finlay HJ, Salvati ME, Adam LP, Gudmundsson O, Hageman MJ. Chen XQ, et al. J Pharm Sci. 2018 May;107(5):1352-1360. doi: 10.1016/j.xphs.2018.01.003. Epub 2018 Jan 6. J Pharm Sci. 2018. PMID: 29317226

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