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Modular design of bi- and multi-specific knob domain fusions.
Kuravsky M, Gibbons GF, Joyce C, Scott-Tucker A, Macpherson A, Lawson ADG. Kuravsky M, et al. Among authors: scott tucker a. Front Immunol. 2024 Mar 27;15:1384467. doi: 10.3389/fimmu.2024.1384467. eCollection 2024. Front Immunol. 2024. PMID: 38605965 Free PMC article.
Identification and characterisation of anti-IL-13 inhibitory single domain antibodies provides new insights into receptor selectivity and attractive opportunities for drug discovery.
Walker K, Baravalle R, Holyfield R, Kalms J, Wright H, Seewooruthun C, Muskett FW, Scott-Tucker A, Merritt A, Henry A, Lawson ADG, Hall G, Prosser C, Carr MD. Walker K, et al. Among authors: scott tucker a. Front Immunol. 2023 Jul 6;14:1216967. doi: 10.3389/fimmu.2023.1216967. eCollection 2023. Front Immunol. 2023. PMID: 37483614 Free PMC article.
Phage Display of Bovine Ultralong CDRH3.
Joyce C, Speight L, Lawson ADG, Scott-Tucker A, Macpherson A. Joyce C, et al. Among authors: scott tucker a. Methods Mol Biol. 2023;2681:83-97. doi: 10.1007/978-1-0716-3279-6_6. Methods Mol Biol. 2023. PMID: 37405644
Serum albumin binding knob domains engineered within a VH framework III bispecific antibody format and as chimeric peptides.
Adams R, Joyce C, Kuravskiy M, Harrison K, Ahdash Z, Balmforth M, Chia K, Marceddu C, Coates M, Snowden J, Goursaud E, Ménochet K, van den Elsen J, Payne RJ, Lawson ADG, Scott-Tucker A, Macpherson A. Adams R, et al. Among authors: scott tucker a. Front Immunol. 2023 May 12;14:1170357. doi: 10.3389/fimmu.2023.1170357. eCollection 2023. Front Immunol. 2023. PMID: 37251411 Free PMC article.
A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF.
Lightwood DJ, Munro RJ, Porter J, McMillan D, Carrington B, Turner A, Scott-Tucker A, Hickford ES, Schmidt A, Fox D 3rd, Maloney A, Ceska T, Bourne T, O'Connell J, Lawson ADG. Lightwood DJ, et al. Among authors: scott tucker a. Nat Commun. 2021 Jan 25;12(1):583. doi: 10.1038/s41467-020-20825-6. Nat Commun. 2021. PMID: 33495445 Free PMC article.
Structurally Mapping Antibody Repertoires.
Krawczyk K, Kelm S, Kovaltsuk A, Galson JD, Kelly D, Trück J, Regep C, Leem J, Wong WK, Nowak J, Snowden J, Wright M, Starkie L, Scott-Tucker A, Shi J, Deane CM. Krawczyk K, et al. Among authors: scott tucker a. Front Immunol. 2018 Jul 23;9:1698. doi: 10.3389/fimmu.2018.01698. eCollection 2018. Front Immunol. 2018. PMID: 30083160 Free PMC article.
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