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Selective glucocorticoid receptor nonsteroidal ligands completely antagonize the dexamethasone mediated induction of enzymes involved in gluconeogenesis and glutamine metabolism.
J Steroid Biochem Mol Biol. 2004 Dec;92(5):345-56. doi: 10.1016/j.jsbmb.2004.10.009. Epub 2005 Jan 21.
J Steroid Biochem Mol Biol. 2004.
PMID: 15698539
Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity.
Smith CJ, Ali A, Balkovec JM, Graham DW, Hammond ML, Patel GF, Rouen GP, Smith SK, Tata JR, Einstein M, Ge L, Harris GS, Kelly TM, Mazur P, Thompson CM, Wang CF, Williamson JM, Miller DK, Pandit S, Santoro JC, Sitlani A, Yamin TT, O'Neill EA, Zaller DM, Carballo-Jane E, Forrest MJ, Luell S.
Smith CJ, et al. Among authors: rouen gp.
Bioorg Med Chem Lett. 2005 Jun 2;15(11):2926-31. doi: 10.1016/j.bmcl.2005.03.027.
Bioorg Med Chem Lett. 2005.
PMID: 15911283
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Discovery of betamethasone 17alpha-carbamates as dissociated glucocorticoid receptor modulators in the rat.
Ali A, Balkovec JM, Greenlee M, Hammond ML, Rouen G, Taylor G, Einstein M, Ge L, Harris G, Kelly TM, Mazur P, Pandit S, Santoro J, Sitlani A, Wang C, Williamson J, Forrest MJ, Carballo-Jane E, Luell S, Lowitz K, Visco D.
Ali A, et al. Among authors: rouen g.
Bioorg Med Chem. 2008 Aug 15;16(16):7535-42. doi: 10.1016/j.bmc.2008.07.037. Epub 2008 Jul 20.
Bioorg Med Chem. 2008.
PMID: 18691892
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Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.
Toney JH, Hammond GG, Fitzgerald PM, Sharma N, Balkovec JM, Rouen GP, Olson SH, Hammond ML, Greenlee ML, Gao YD.
Toney JH, et al. Among authors: rouen gp.
J Biol Chem. 2001 Aug 24;276(34):31913-8. doi: 10.1074/jbc.M104742200. Epub 2001 Jun 4.
J Biol Chem. 2001.
PMID: 11390410
Free article.
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Dicationic 2-fluorenonylcarbapenems: potent anti-MRS agents with improved solubility and pharmacokinetic properties.
Greenlee ML, Laub JB, Rouen GP, DiNinno F, Hammond ML, Huber JL, Sundelof JG, Hammond GG.
Greenlee ML, et al. Among authors: rouen gp.
Bioorg Med Chem Lett. 1999 Nov 15;9(22):3225-30. doi: 10.1016/s0960-894x(99)00567-3.
Bioorg Med Chem Lett. 1999.
PMID: 10576693
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