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Cardiac adenoviral S100A1 gene delivery rescues failing myocardium.
Most P, Pleger ST, Völkers M, Heidt B, Boerries M, Weichenhan D, Löffler E, Janssen PM, Eckhart AD, Martini J, Williams ML, Katus HA, Remppis A, Koch WJ. Most P, et al. Among authors: remppis a. J Clin Invest. 2004 Dec;114(11):1550-63. doi: 10.1172/JCI21454. J Clin Invest. 2004. PMID: 15578088 Free PMC article.
Endothelial S100A1 modulates vascular function via nitric oxide.
Pleger ST, Harris DM, Shan C, Vinge LE, Chuprun JK, Berzins B, Pleger W, Druckman C, Völkers M, Heierhorst J, Øie E, Remppis A, Katus HA, Scalia R, Eckhart AD, Koch WJ, Most P. Pleger ST, et al. Among authors: remppis a. Circ Res. 2008 Apr 11;102(7):786-94. doi: 10.1161/CIRCRESAHA.108.172031. Epub 2008 Feb 21. Circ Res. 2008. PMID: 18292599
Therapeutic safety of high myocardial expression levels of the molecular inotrope S100A1 in a preclinical heart failure model.
Weber C, Neacsu I, Krautz B, Schlegel P, Sauer S, Raake P, Ritterhoff J, Jungmann A, Remppis AB, Stangassinger M, Koch WJ, Katus HA, Müller OJ, Most P, Pleger ST. Weber C, et al. Among authors: remppis ab. Gene Ther. 2014 Feb;21(2):131-8. doi: 10.1038/gt.2013.63. Epub 2013 Dec 5. Gene Ther. 2014. PMID: 24305416 Free PMC article.
The C terminus (amino acids 75-94) and the linker region (amino acids 42-54) of the Ca2+-binding protein S100A1 differentially enhance sarcoplasmic Ca2+ release in murine skinned skeletal muscle fibers.
Most P, Remppis A, Weber C, Bernotat J, Ehlermann P, Pleger ST, Kirsch W, Weber M, Uttenweiler D, Smith GL, Katus HA, Fink RH. Most P, et al. Among authors: remppis a. J Biol Chem. 2003 Jul 18;278(29):26356-64. doi: 10.1074/jbc.M303338200. Epub 2003 Apr 28. J Biol Chem. 2003. PMID: 12721284 Free article.
Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
Most P, Remppis A, Pleger ST, Löffler E, Ehlermann P, Bernotat J, Kleuss C, Heierhorst J, Ruiz P, Witt H, Karczewski P, Mao L, Rockman HA, Duncan SJ, Katus HA, Koch WJ. Most P, et al. Among authors: remppis a. J Biol Chem. 2003 Sep 5;278(36):33809-17. doi: 10.1074/jbc.M301788200. Epub 2003 May 30. J Biol Chem. 2003. PMID: 12777394 Free article.
Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2).
Most P, Boerries M, Eicher C, Schweda C, Ehlermann P, Pleger ST, Loeffler E, Koch WJ, Katus HA, Schoenenberger CA, Remppis A. Most P, et al. Among authors: remppis a. J Biol Chem. 2003 Nov 28;278(48):48404-12. doi: 10.1074/jbc.M308587200. Epub 2003 Sep 6. J Biol Chem. 2003. PMID: 12960148 Free article.
120 results