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S100A1: a regulator of myocardial contractility.
Most P, Bernotat J, Ehlermann P, Pleger ST, Reppel M, Börries M, Niroomand F, Pieske B, Janssen PM, Eschenhagen T, Karczewski P, Smith GL, Koch WJ, Katus HA, Remppis A. Most P, et al. Among authors: koch wj. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13889-94. doi: 10.1073/pnas.241393598. Proc Natl Acad Sci U S A. 2001. PMID: 11717446 Free PMC article.
Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
Most P, Remppis A, Pleger ST, Löffler E, Ehlermann P, Bernotat J, Kleuss C, Heierhorst J, Ruiz P, Witt H, Karczewski P, Mao L, Rockman HA, Duncan SJ, Katus HA, Koch WJ. Most P, et al. Among authors: koch wj. J Biol Chem. 2003 Sep 5;278(36):33809-17. doi: 10.1074/jbc.M301788200. Epub 2003 May 30. J Biol Chem. 2003. PMID: 12777394 Free article.
Sealing the leak, healing the heart.
Most P, Koch WJ. Most P, et al. Among authors: koch wj. Nat Med. 2003 Aug;9(8):993-4. doi: 10.1038/nm0803-993. Nat Med. 2003. PMID: 12894157 No abstract available.
Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2).
Most P, Boerries M, Eicher C, Schweda C, Ehlermann P, Pleger ST, Loeffler E, Koch WJ, Katus HA, Schoenenberger CA, Remppis A. Most P, et al. Among authors: koch wj. J Biol Chem. 2003 Nov 28;278(48):48404-12. doi: 10.1074/jbc.M308587200. Epub 2003 Sep 6. J Biol Chem. 2003. PMID: 12960148 Free article.
S100A1 gene transfer: a strategy to strengthen engineered cardiac grafts.
Remppis A, Pleger ST, Most P, Lindenkamp J, Ehlermann P, Schweda C, Löffler E, Weichenhan D, Zimmermann W, Eschenhagen T, Koch WJ, Katus HA. Remppis A, et al. Among authors: koch wj. J Gene Med. 2004 Apr;6(4):387-94. doi: 10.1002/jgm.513. J Gene Med. 2004. PMID: 15079813
Cardiac adenoviral S100A1 gene delivery rescues failing myocardium.
Most P, Pleger ST, Völkers M, Heidt B, Boerries M, Weichenhan D, Löffler E, Janssen PM, Eckhart AD, Martini J, Williams ML, Katus HA, Remppis A, Koch WJ. Most P, et al. Among authors: koch wj. J Clin Invest. 2004 Dec;114(11):1550-63. doi: 10.1172/JCI21454. J Clin Invest. 2004. PMID: 15578088 Free PMC article.
S100A1 gene therapy preserves in vivo cardiac function after myocardial infarction.
Pleger ST, Remppis A, Heidt B, Völkers M, Chuprun JK, Kuhn M, Zhou RH, Gao E, Szabo G, Weichenhan D, Müller OJ, Eckhart AD, Katus HA, Koch WJ, Most P. Pleger ST, et al. Among authors: koch wj. Mol Ther. 2005 Dec;12(6):1120-9. doi: 10.1016/j.ymthe.2005.08.002. Epub 2005 Sep 15. Mol Ther. 2005. PMID: 16168714 Free article.
518 results