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Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate.
Bioorg Med Chem. 2005 Jan 17;13(2):425-32. doi: 10.1016/j.bmc.2004.10.008.
Bioorg Med Chem. 2005.
PMID: 15598563
Non-peptidic inhibitors of human chymase. Synthesis, structure-activity relationships, and pharmacokinetic profiles of a series of 5-amino-6-oxo-1,6-dihydropyrimidine-containing trifluoromethyl ketones.
Akahoshi F, Ashimori A, Yoshimura T, Imada T, Nakajima M, Mitsutomi N, Kuwahara S, Ohtsuka T, Fukaya C, Miyazaki M, Nakamura N.
Akahoshi F, et al. Among authors: mitsutomi n.
Bioorg Med Chem. 2001 Feb;9(2):301-15. doi: 10.1016/s0968-0896(00)00244-3.
Bioorg Med Chem. 2001.
PMID: 11249123
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Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic alpha-keto heterocycles as novel inhibitors of human chymase.
Akahoshi F, Ashimori A, Sakashita H, Yoshimura T, Imada T, Nakajima M, Mitsutomi N, Kuwahara S, Ohtsuka T, Fukaya C, Miyazaki M, Nakamura N.
Akahoshi F, et al. Among authors: mitsutomi n.
J Med Chem. 2001 Apr 12;44(8):1286-96. doi: 10.1021/jm000496v.
J Med Chem. 2001.
PMID: 11312927
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Synthesis, structure-activity relationships, and pharmacokinetic profiles of nonpeptidic difluoromethylene ketones as novel inhibitors of human chymase.
Akahoshi F, Ashimori A, Sakashita H, Yoshimura T, Eda M, Imada T, Nakajima M, Mitsutomi N, Kuwahara S, Ohtsuka T, Fukaya C, Miyazaki M, Nakamura N.
Akahoshi F, et al. Among authors: mitsutomi n.
J Med Chem. 2001 Apr 12;44(8):1297-304. doi: 10.1021/jm000497n.
J Med Chem. 2001.
PMID: 11312928
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Effects of endogenous and exogenous nitric oxide on endothelin-1 production in cultured vascular endothelial cells.
Mitsutomi N, Akashi C, Odagiri J, Matsumura Y.
Mitsutomi N, et al.
Eur J Pharmacol. 1999 Jan 1;364(1):65-73. doi: 10.1016/s0014-2999(98)00806-1.
Eur J Pharmacol. 1999.
PMID: 9920186
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Endothelin-1 secretion from cultured vascular endothelial cells of DOCA-salt hypertensive rats.
Takada K, Matsumura Y, Dohmen S, Mitsutomi N, Takaoka M, Morimoto S.
Takada K, et al. Among authors: mitsutomi n.
Life Sci. 1996;59(9):PL111-6. doi: 10.1016/0024-3205(96)00366-9.
Life Sci. 1996.
PMID: 8761033
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Induced pluripotent stem cell-based assays recapture multiple properties of human astrocytes.
Nonaka H, Kondo T, Suga M, Yamanaka R, Sagara Y, Tsukita K, Mitsutomi N, Homma K, Saito R, Miyoshi F, Ohzeki H, Okuyama M, Inoue H.
Nonaka H, et al. Among authors: mitsutomi n.
J Cell Mol Med. 2024 Apr;28(7):e18214. doi: 10.1111/jcmm.18214.
J Cell Mol Med. 2024.
PMID: 38509731
Free PMC article.
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