Hughes C - Search Results

1

Three's company: component structures bring a closer view of tripartite drug efflux pumps.

Eswaran J, Koronakis E, Higgins MK, Hughes C, Koronakis V. Eswaran J, et al. Among authors: hughes c. Curr Opin Struct Biol. 2004 Dec;14(6):741-7. doi: 10.1016/j.sbi.2004.10.003. Curr Opin Struct Biol. 2004. PMID: 15582398 Review.

2

Structure of the periplasmic component of a bacterial drug efflux pump.

Higgins MK, Bokma E, Koronakis E, Hughes C, Koronakis V. Higgins MK, et al. Among authors: hughes c. Proc Natl Acad Sci U S A. 2004 Jul 6;101(27):9994-9. doi: 10.1073/pnas.0400375101. Epub 2004 Jun 28. Proc Natl Acad Sci U S A. 2004. PMID: 15226509 Free PMC article.

3

Interactions underlying assembly of the Escherichia coli AcrAB-TolC multidrug efflux system.

Touzé T, Eswaran J, Bokma E, Koronakis E, Hughes C, Koronakis V. Touzé T, et al. Among authors: hughes c. Mol Microbiol. 2004 Jul;53(2):697-706. doi: 10.1111/j.1365-2958.2004.04158.x. Mol Microbiol. 2004. PMID: 15228545 Free article.

4

Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug efflux protein TolC.

Higgins MK, Eswaran J, Edwards P, Schertler GF, Hughes C, Koronakis V. Higgins MK, et al. Among authors: hughes c. J Mol Biol. 2004 Sep 17;342(3):697-702. doi: 10.1016/j.jmb.2004.07.088. J Mol Biol. 2004. PMID: 15342230

5

Directed evolution of a bacterial efflux pump: adaptation of the E. coli TolC exit duct to the Pseudomonas MexAB translocase.

Bokma E, Koronakis E, Lobedanz S, Hughes C, Koronakis V. Bokma E, et al. Among authors: hughes c. FEBS Lett. 2006 Oct 2;580(22):5339-43. doi: 10.1016/j.febslet.2006.09.005. Epub 2006 Sep 12. FEBS Lett. 2006. PMID: 16979625 Free article.

6

A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps.

Lobedanz S, Bokma E, Symmons MF, Koronakis E, Hughes C, Koronakis V. Lobedanz S, et al. Among authors: hughes c. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4612-7. doi: 10.1073/pnas.0610160104. Epub 2007 Mar 5. Proc Natl Acad Sci U S A. 2007. PMID: 17360572 Free PMC article.

7

The assembled structure of a complete tripartite bacterial multidrug efflux pump.

Symmons MF, Bokma E, Koronakis E, Hughes C, Koronakis V. Symmons MF, et al. Among authors: hughes c. Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):7173-8. doi: 10.1073/pnas.0900693106. Epub 2009 Apr 2. Proc Natl Acad Sci U S A. 2009. PMID: 19342493 Free PMC article.

8

Structures of sequential open states in a symmetrical opening transition of the TolC exit duct.

Pei XY, Hinchliffe P, Symmons MF, Koronakis E, Benz R, Hughes C, Koronakis V. Pei XY, et al. Among authors: hughes c. Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):2112-7. doi: 10.1073/pnas.1012588108. Epub 2011 Jan 18. Proc Natl Acad Sci U S A. 2011. PMID: 21245342 Free PMC article.

9

Structure and operation of bacterial tripartite pumps.

Hinchliffe P, Symmons MF, Hughes C, Koronakis V. Hinchliffe P, et al. Among authors: hughes c. Annu Rev Microbiol. 2013;67:221-42. doi: 10.1146/annurev-micro-092412-155718. Epub 2013 Jun 26. Annu Rev Microbiol. 2013. PMID: 23808339 Review.

10

Locking TolC entrance helices to prevent protein translocation by the bacterial type I export apparatus.

Eswaran J, Hughes C, Koronakis V. Eswaran J, et al. Among authors: hughes c. J Mol Biol. 2003 Mar 21;327(2):309-15. doi: 10.1016/s0022-2836(03)00116-5. J Mol Biol. 2003. PMID: 12628238

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