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The induction of CCN2 by TGFbeta1 involves Ets-1.
Van Beek JP, Kennedy L, Rockel JS, Bernier SM, Leask A. Van Beek JP, et al. Arthritis Res Ther. 2006;8(2):R36. doi: 10.1186/ar1890. Epub 2006 Jan 16. Arthritis Res Ther. 2006. PMID: 16469114 Free PMC article.
Matrix contraction by dermal fibroblasts requires transforming growth factor-beta/activin-linked kinase 5, heparan sulfate-containing proteoglycans, and MEK/ERK: insights into pathological scarring in chronic fibrotic disease.
Chen Y, Shi-Wen X, van Beek J, Kennedy L, McLeod M, Renzoni EA, Bou-Gharios G, Wilcox-Adelman S, Goetinck PF, Eastwood M, Black CM, Abraham DJ, Leask A. Chen Y, et al. Am J Pathol. 2005 Dec;167(6):1699-711. doi: 10.1016/s0002-9440(10)61252-7. Am J Pathol. 2005. PMID: 16314481 Free PMC article.