Waring JF - Search Results

1

Toxicogenomics in drug discovery: from preclinical studies to clinical trials.

Yang Y, Blomme EA, Waring JF. Yang Y, et al. Among authors: waring jf. Chem Biol Interact. 2004 Nov 1;150(1):71-85. doi: 10.1016/j.cbi.2004.09.013. Chem Biol Interact. 2004. PMID: 15522262 Review.

2

Use of toxicogenomics to understand mechanisms of drug-induced hepatotoxicity during drug discovery and development.

Blomme EA, Yang Y, Waring JF. Blomme EA, et al. Among authors: waring jf. Toxicol Lett. 2009 Apr 10;186(1):22-31. doi: 10.1016/j.toxlet.2008.09.017. Epub 2008 Oct 17. Toxicol Lett. 2009. PMID: 18996174 Review.

3

Microarray analysis of lipopolysaccharide potentiation of trovafloxacin-induced liver injury in rats suggests a role for proinflammatory chemokines and neutrophils.

Waring JF, Liguori MJ, Luyendyk JP, Maddox JF, Ganey PE, Stachlewitz RF, North C, Blomme EA, Roth RA. Waring JF, et al. J Pharmacol Exp Ther. 2006 Mar;316(3):1080-7. doi: 10.1124/jpet.105.096347. Epub 2005 Nov 18. J Pharmacol Exp Ther. 2006. PMID: 16299187

4

Development of a toxicogenomics in vitro assay for the efficient characterization of compounds.

Yang Y, Abel SJ, Ciurlionis R, Waring JF. Yang Y, et al. Among authors: waring jf. Pharmacogenomics. 2006 Mar;7(2):177-86. doi: 10.2217/14622416.7.2.177. Pharmacogenomics. 2006. PMID: 16515397

5

N-{3-[2-(4-alkoxyphenoxy)thiazol-5-yl]-1-methylprop-2-ynyl}carboxy derivatives as acetyl-coA carboxylase inhibitors--improvement of cardiovascular and neurological liabilities via structural modifications.

Gu YG, Weitzberg M, Clark RF, Xu X, Li Q, Lubbers NL, Yang Y, Beno DW, Widomski DL, Zhang T, Hansen TM, Keyes RF, Waring JF, Carroll SL, Wang X, Wang R, Healan-Greenberg CH, Blomme EA, Beutel BA, Sham HL, Camp HS. Gu YG, et al. Among authors: waring jf. J Med Chem. 2007 Mar 8;50(5):1078-82. doi: 10.1021/jm070035a. Epub 2007 Feb 14. J Med Chem. 2007. PMID: 17298049

6

Trovafloxacin-induced gene expression changes in liver-derived in vitro systems: comparison of primary human hepatocytes to HepG2 cells.

Liguori MJ, Blomme EA, Waring JF. Liguori MJ, et al. Among authors: waring jf. Drug Metab Dispos. 2008 Feb;36(2):223-33. doi: 10.1124/dmd.107.017608. Epub 2007 Oct 29. Drug Metab Dispos. 2008. PMID: 17967932

7

A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.

Healan-Greenberg C, Waring JF, Kempf DJ, Blomme EA, Tirona RG, Kim RB. Healan-Greenberg C, et al. Among authors: waring jf. Drug Metab Dispos. 2008 Mar;36(3):500-7. doi: 10.1124/dmd.107.019547. Epub 2007 Dec 20. Drug Metab Dispos. 2008. PMID: 18096673

8

Evaluation of the effects of serial phlebotomy on the transcriptome of major tissues and on the response to toxicants in rats.

Blomme EA, Ciurlionis R, Marsh KC, Waring JF, Yang Y. Blomme EA, et al. Among authors: waring jf. Toxicol Lett. 2008 Jan 30;176(2):138-48. doi: 10.1016/j.toxlet.2007.09.014. Epub 2007 Oct 9. Toxicol Lett. 2008. PMID: 18164877

9

Use of traditional end points and gene dysregulation to understand mechanisms of toxicity: toxicogenomics in mechanistic toxicology.

Buck WR, Waring JF, Blomme EA. Buck WR, et al. Among authors: waring jf. Methods Mol Biol. 2008;460:23-44. doi: 10.1007/978-1-60327-048-9_2. Methods Mol Biol. 2008. PMID: 18449481

10

Liver transcriptomic changes associated with ritonavir-induced hyperlipidemia in sensitive and resistant strains of rats.

Yang Y, Dahly-Vernon AJ, Blomme EA, Lai-Zhang J, Kempf DJ, Marsh KC, Harrington YA, Nye SH, Evans DL, Roman RJ, Jacob HJ, Waring JF. Yang Y, et al. Among authors: waring jf. Vet J. 2010 Jul;185(1):75-82. doi: 10.1016/j.tvjl.2010.04.017. Epub 2010 May 23. Vet J. 2010. PMID: 20547082

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