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PAX4 gene variations predispose to ketosis-prone diabetes.
Mauvais-Jarvis F, Smith SB, Le May C, Leal SM, Gautier JF, Molokhia M, Riveline JP, Rajan AS, Kevorkian JP, Zhang S, Vexiau P, German MS, Vaisse C. Mauvais-Jarvis F, et al. Among authors: le may c. Hum Mol Genet. 2004 Dec 15;13(24):3151-9. doi: 10.1093/hmg/ddh341. Epub 2004 Oct 27. Hum Mol Genet. 2004. PMID: 15509590 Free PMC article.
Estrogen receptor activation reduces lipid synthesis in pancreatic islets and prevents β cell failure in rodent models of type 2 diabetes.
Tiano JP, Delghingaro-Augusto V, Le May C, Liu S, Kaw MK, Khuder SS, Latour MG, Bhatt SA, Korach KS, Najjar SM, Prentki M, Mauvais-Jarvis F. Tiano JP, et al. Among authors: le may c. J Clin Invest. 2011 Aug;121(8):3331-42. doi: 10.1172/JCI44564. Epub 2011 Jul 11. J Clin Invest. 2011. PMID: 21747171 Free PMC article.
The Role of Estrogens in Pancreatic Islet Physiopathology.
Mauvais-Jarvis F, Le May C, Tiano JP, Liu S, Kilic-Berkmen G, Kim JH. Mauvais-Jarvis F, et al. Among authors: le may c. Adv Exp Med Biol. 2017;1043:385-399. doi: 10.1007/978-3-319-70178-3_18. Adv Exp Med Biol. 2017. PMID: 29224104 Review.
Circulating PCSK9 levels are not associated with the severity of hepatic steatosis and NASH in a high-risk population.
Wargny M, Ducluzeau PH, Petit JM, Le May C, Smati S, Arnaud L, Pichelin M, Bouillet B, Lannes A, Blanchet O, Lefebvre P, Francque S, Van Gaal L, Staels B, Vergès B, Boursier J, Cariou B. Wargny M, et al. Among authors: le may c. Atherosclerosis. 2018 Nov;278:82-90. doi: 10.1016/j.atherosclerosis.2018.09.008. Epub 2018 Sep 13. Atherosclerosis. 2018. PMID: 30261472
PCSK9 is expressed in pancreatic delta-cells and does not alter insulin secretion.
Langhi C, Le May C, Gmyr V, Vandewalle B, Kerr-Conte J, Krempf M, Pattou F, Costet P, Cariou B. Langhi C, et al. Among authors: le may c. Biochem Biophys Res Commun. 2009 Dec 25;390(4):1288-93. doi: 10.1016/j.bbrc.2009.10.138. Epub 2009 Oct 28. Biochem Biophys Res Commun. 2009. PMID: 19878649
105 results