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The GABA(B2) subunit is critical for the trafficking and function of native GABA(B) receptors.
Thuault SJ, Brown JT, Sheardown SA, Jourdain S, Fairfax B, Spencer JP, Restituito S, Nation JH, Topps S, Medhurst AD, Randall AD, Couve A, Moss SJ, Collingridge GL, Pangalos MN, Davies CH, Calver AR. Thuault SJ, et al. Among authors: brown jt. Biochem Pharmacol. 2004 Oct 15;68(8):1655-66. doi: 10.1016/j.bcp.2004.07.032. Biochem Pharmacol. 2004. PMID: 15451409
Gabapentin is not a GABAB receptor agonist.
Lanneau C, Green A, Hirst WD, Wise A, Brown JT, Donnier E, Charles KJ, Wood M, Davies CH, Pangalos MN. Lanneau C, et al. Among authors: brown jt. Neuropharmacology. 2001 Dec;41(8):965-75. doi: 10.1016/s0028-3908(01)00140-x. Neuropharmacology. 2001. PMID: 11747901
LPA1 receptor-deficient mice have phenotypic changes observed in psychiatric disease.
Harrison SM, Reavill C, Brown G, Brown JT, Cluderay JE, Crook B, Davies CH, Dawson LA, Grau E, Heidbreder C, Hemmati P, Hervieu G, Howarth A, Hughes ZA, Hunter AJ, Latcham J, Pickering S, Pugh P, Rogers DC, Shilliam CS, Maycox PR. Harrison SM, et al. Among authors: brown g, brown jt. Mol Cell Neurosci. 2003 Dec;24(4):1170-9. doi: 10.1016/j.mcn.2003.09.001. Mol Cell Neurosci. 2003. PMID: 14697676
290 results