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2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: design, synthesis, and SAR studies.
Meyers C, Yáñez M, Elmaatougi A, Verhelst T, Coelho A, Fraiz N, Lemière GL, García-Mera X, Laguna R, Cano E, Maes BU, Sotelo E. Meyers C, et al. Among authors: lemiere gl. Bioorg Med Chem Lett. 2008 Jan 15;18(2):793-7. doi: 10.1016/j.bmcl.2007.11.034. Epub 2007 Nov 17. Bioorg Med Chem Lett. 2008. PMID: 18053717
Synthesis, cytotoxicity, and antiplasmodial and antitrypanosomal activity of new neocryptolepine derivatives.
Jonckers TH, van Miert S, Cimanga K, Bailly C, Colson P, De Pauw-Gillet MC, van den Heuvel H, Claeys M, Lemière F, Esmans EL, Rozenski J, Quirijnen L, Maes L, Dommisse R, Lemière GL, Vlietinck A, Pieters L. Jonckers TH, et al. Among authors: lemiere gl. J Med Chem. 2002 Aug 1;45(16):3497-508. doi: 10.1021/jm011102i. J Med Chem. 2002. PMID: 12139461
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