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Defective apoptosis and B-cell lymphomas in mice with p53 point mutation at Ser 23.
MacPherson D, Kim J, Kim T, Rhee BK, Van Oostrom CT, DiTullio RA, Venere M, Halazonetis TD, Bronson R, De Vries A, Fleming M, Jacks T. MacPherson D, et al. Among authors: van oostrom ct. EMBO J. 2004 Sep 15;23(18):3689-99. doi: 10.1038/sj.emboj.7600363. Epub 2004 Sep 2. EMBO J. 2004. PMID: 15343266 Free PMC article.
Lack of p53 Ser389 phosphorylation predisposes mice to develop 2-acetylaminofluorene-induced bladder tumors but not ionizing radiation-induced lymphomas.
Hoogervorst EM, Bruins W, Zwart E, van Oostrom CT, van den Aardweg GJ, Beems RB, van den Berg J, Jacks T, van Steeg H, de Vries A. Hoogervorst EM, et al. Among authors: van den aardweg gj, van den berg j, van steeg h, van oostrom ct. Cancer Res. 2005 May 1;65(9):3610-6. doi: 10.1158/0008-5472.CAN-04-4328. Cancer Res. 2005. PMID: 15867355
p53 heterozygosity results in an increased 2-acetylaminofluorene-induced urinary bladder but not liver tumor response in DNA repair-deficient Xpa mice.
Hoogervorst EM, van Oostrom CT, Beems RB, van Benthem J, Gielis S, Vermeulen JP, Wester PW, Vos JG, de Vries A, van Steeg H. Hoogervorst EM, et al. Among authors: van steeg h, van benthem j, van oostrom ct. Cancer Res. 2004 Aug 1;64(15):5118-26. doi: 10.1158/0008-5472.CAN-04-0350. Cancer Res. 2004. PMID: 15289314
2-AAF-induced tumor development in nucleotide excision repair-deficient mice is associated with a defect in global genome repair but not with transcription coupled repair.
Hoogervorst EM, van Oostrom CT, Beems RB, van Benthem J, van den Berg J, van Kreijl CF, Vos JG, de Vries A, van Steeg H. Hoogervorst EM, et al. Among authors: van den berg j, van kreijl cf, van steeg h, van benthem j, van oostrom ct. DNA Repair (Amst). 2005 Jan 2;4(1):3-9. doi: 10.1016/j.dnarep.2004.08.009. DNA Repair (Amst). 2005. PMID: 15533832
Combined oral benzo[a]pyrene and inhalatory ozone exposure have no effect on lung tumor development in DNA repair-deficient Xpa mice.
Hoogervorst EM, de Vries A, Beems RB, van Oostrom CT, Wester PW, Vos JG, Bruins W, Roodbergen M, Cassee FR, Vijg J, van Schooten FJ, van Steeg H. Hoogervorst EM, et al. Among authors: van steeg h, van schooten fj, van oostrom ct. Carcinogenesis. 2003 Mar;24(3):613-9. doi: 10.1093/carcin/24.3.613. Carcinogenesis. 2003. PMID: 12663525
Evaluation of benzo(a)pyrene-induced gene mutations in male germ cells.
Verhofstad N, van Oostrom CT, Zwart E, Maas LM, van Benthem J, van Schooten FJ, van Steeg H, Godschalk RW. Verhofstad N, et al. Among authors: van steeg h, van schooten fj, van benthem j, van oostrom ct. Toxicol Sci. 2011 Jan;119(1):218-23. doi: 10.1093/toxsci/kfq325. Epub 2010 Oct 20. Toxicol Sci. 2011. PMID: 20961952
55 results