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Lidocaine: a foot in the door of the inner vestibule prevents ultra-slow inactivation of a voltage-gated sodium channel.
Mol Pharmacol. 2004 Sep;66(3):648-57. doi: 10.1124/mol.66.3..
Mol Pharmacol. 2004.
PMID: 15322257
Selectivity filter residues contribute unequally to pore stabilization in voltage-gated sodium channels.
Hilber K, Sandtner W, Zarrabi T, Zebedin E, Kudlacek O, Fozzard HA, Todt H.
Hilber K, et al. Among authors: zarrabi t.
Biochemistry. 2005 Oct 25;44(42):13874-82. doi: 10.1021/bi0511944.
Biochemistry. 2005.
PMID: 16229476
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Speeding the recovery from ultraslow inactivation of voltage-gated Na+ channels by metal ion binding to the selectivity filter: a foot-on-the-door?
Szendroedi J, Sandtner W, Zarrabi T, Zebedin E, Hilber K, Dudley SC Jr, Fozzard HA, Todt H.
Szendroedi J, et al. Among authors: zarrabi t.
Biophys J. 2007 Dec 15;93(12):4209-24. doi: 10.1529/biophysj.107.104794. Epub 2007 Aug 24.
Biophys J. 2007.
PMID: 17720727
Free PMC article.
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A molecular switch between the outer and the inner vestibules of the voltage-gated Na+ channel.
Zarrabi T, Cervenka R, Sandtner W, Lukacs P, Koenig X, Hilber K, Mille M, Lipkind GM, Fozzard HA, Todt H.
Zarrabi T, et al.
J Biol Chem. 2010 Dec 10;285(50):39458-70. doi: 10.1074/jbc.M110.132886. Epub 2010 Oct 6.
J Biol Chem. 2010.
PMID: 20926383
Free PMC article.
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C2C12 skeletal muscle cells adopt cardiac-like sodium current properties in a cardiac cell environment.
Zebedin E, Mille M, Speiser M, Zarrabi T, Sandtner W, Latzenhofer B, Todt H, Hilber K.
Zebedin E, et al. Among authors: zarrabi t.
Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H439-50. doi: 10.1152/ajpheart.00119.2006. Epub 2006 Sep 15.
Am J Physiol Heart Circ Physiol. 2007.
PMID: 16980339
Free article.
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The outer vestibule of the Na+ channel-toxin receptor and modulator of permeation as well as gating.
Cervenka R, Zarrabi T, Lukacs P, Todt H.
Cervenka R, et al. Among authors: zarrabi t.
Mar Drugs. 2010 Apr 21;8(4):1373-93. doi: 10.3390/md8041373.
Mar Drugs. 2010.
PMID: 20479982
Free PMC article.
Review.
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Exploring the structure of the voltage-gated Na+ channel by an engineered drug access pathway to the receptor site for local anesthetics.
Lukacs P, Gawali VS, Cervenka R, Ke S, Koenig X, Rubi L, Zarrabi T, Hilber K, Stary-Weinzinger A, Todt H.
Lukacs P, et al. Among authors: zarrabi t.
J Biol Chem. 2014 Aug 1;289(31):21770-81. doi: 10.1074/jbc.M113.541763. Epub 2014 Jun 19.
J Biol Chem. 2014.
PMID: 24947510
Free PMC article.
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Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na+ channels: mechanistic insights from recent crystal structures.
Cervenka R, Lukacs P, Gawali VS, Ke S, Koenig X, Rubi L, Zarrabi T, Hilber K, Sandtner W, Stary-Weinzinger A, Todt H.
Cervenka R, et al. Among authors: zarrabi t.
Sci Rep. 2018 Jan 12;8(1):631. doi: 10.1038/s41598-017-18919-1.
Sci Rep. 2018.
PMID: 29330525
Free PMC article.
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