Neutrophil elastase stimulates MUC1 gene expression through increased Sp1 binding to the MUC1 promoter.
Kuwahara I, Lillehoj EP, Hisatsune A, Lu W, Isohama Y, Miyata T, Kim KC.
Kuwahara I, et al. Among authors: lillehoj ep.
Am J Physiol Lung Cell Mol Physiol. 2005 Aug;289(2):L355-62. doi: 10.1152/ajplung.00040.2005. Epub 2005 Apr 22.
Am J Physiol Lung Cell Mol Physiol. 2005.
PMID: 15849214
Free article.
We previously reported MUC1 was a cell surface receptor for Pseudomonas aeruginosa, and binding of bacteria to cells was significantly reduced by pretreatment with neutrophil elastase (NE) (Lillehoj EP, Hyun SW, Kim BT, Zhang XG, Lee DI, Rowland S, and Kim KC. ...
We previously reported MUC1 was a cell surface receptor for Pseudomonas aeruginosa, and binding of bacteria to cells was significantly reduc …