Osslund T - Search Results

1

N-Aryl-gamma-lactams as integrin alphavbeta3 antagonists.

Xi N, Arvedson S, Eisenberg S, Han N, Handley M, Huang L, Huang Q, Kiselyov A, Liu Q, Lu Y, Nunez G, Osslund T, Powers D, Tasker AS, Wang L, Xiang T, Xu S, Zhang J, Zhu J, Kendall R, Dominguez C. Xi N, et al. Among authors: osslund t. Bioorg Med Chem Lett. 2004 Jun 7;14(11):2905-9. doi: 10.1016/j.bmcl.2004.03.033. Bioorg Med Chem Lett. 2004. PMID: 15125957

2

Design and synthesis of quinolin-2(1H)-one derivatives as potent CDK5 inhibitors.

Zhong W, Liu H, Kaller MR, Henley C, Magal E, Nguyen T, Osslund TD, Powers D, Rzasa RM, Wang HL, Wang W, Xiong X, Zhang J, Norman MH. Zhong W, et al. Among authors: osslund td. Bioorg Med Chem Lett. 2007 Oct 1;17(19):5384-9. doi: 10.1016/j.bmcl.2007.07.045. Epub 2007 Aug 6. Bioorg Med Chem Lett. 2007. PMID: 17709247

3

Structure-activity relationships of 3,4-dihydro-1H-quinazolin-2-one derivatives as potential CDK5 inhibitors.

Rzasa RM, Kaller MR, Liu G, Magal E, Nguyen TT, Osslund TD, Powers D, Santora VJ, Viswanadhan VN, Wang HL, Xiong X, Zhong W, Norman MH. Rzasa RM, et al. Among authors: osslund td. Bioorg Med Chem. 2007 Oct 15;15(20):6574-95. doi: 10.1016/j.bmc.2007.07.005. Epub 2007 Jul 25. Bioorg Med Chem. 2007. PMID: 17697781

4

Crystal structure of murine 11 beta-hydroxysteroid dehydrogenase 1: an important therapeutic target for diabetes.

Zhang J, Osslund TD, Plant MH, Clogston CL, Nybo RE, Xiong F, Delaney JM, Jordan SR. Zhang J, et al. Among authors: osslund td. Biochemistry. 2005 May 10;44(18):6948-57. doi: 10.1021/bi047599q. Biochemistry. 2005. PMID: 15865440

5

Efficiency of signalling through cytokine receptors depends critically on receptor orientation.

Syed RS, Reid SW, Li C, Cheetham JC, Aoki KH, Liu B, Zhan H, Osslund TD, Chirino AJ, Zhang J, Finer-Moore J, Elliott S, Sitney K, Katz BA, Matthews DJ, Wendoloski JJ, Egrie J, Stroud RM. Syed RS, et al. Among authors: osslund td. Nature. 1998 Oct 1;395(6701):511-6. doi: 10.1038/26773. Nature. 1998. PMID: 9774108

6

Enhanced stability of recombinant keratinocyte growth factor by mutagenesis.

Hsu E, Osslund T, Nybo R, Chen BL, Kenney WC, Morris CF, Arakawa T, Narhi LO. Hsu E, et al. Among authors: osslund t. Protein Eng Des Sel. 2006 Apr;19(4):147-53. doi: 10.1093/protein/gzj013. Epub 2006 Feb 14. Protein Eng Des Sel. 2006. PMID: 16478751

7

Correlation between the 1.6 A crystal structure and mutational analysis of keratinocyte growth factor.

Osslund TD, Syed R, Singer E, Hsu EW, Nybo R, Chen BL, Harvey T, Arakawa T, Narhi LO, Chirino A, Morris CF. Osslund TD, et al. Protein Sci. 1998 Aug;7(8):1681-90. doi: 10.1002/pro.5560070803. Protein Sci. 1998. PMID: 10082365 Free PMC article.

8

Conformational changes in G-CSF/Receptor complex as investigated by isotope-edited FTIR spectroscopy.

Li T, Horan T, Osslund T, Stearns G, Arakawa T. Li T, et al. Among authors: osslund t. Biochemistry. 1997 Jul 22;36(29):8849-57. doi: 10.1021/bi962713t. Biochemistry. 1997. PMID: 9220971

9

The intermolecular disulfide bridge of human glial cell line-derived neurotrophic factor: its selective reduction and biological activity of the modified protein.

Hui JO, Woo G, Chow DT, Katta V, Osslund T, Haniu M. Hui JO, et al. Among authors: osslund t. J Protein Chem. 1999 Jul;18(5):585-93. doi: 10.1023/a:1020607501910. J Protein Chem. 1999. PMID: 10524776

10

Structure of the active core of human stem cell factor and analysis of binding to its receptor kit.

Jiang X, Gurel O, Mendiaz EA, Stearns GW, Clogston CL, Lu HS, Osslund TD, Syed RS, Langley KE, Hendrickson WA. Jiang X, et al. Among authors: osslund td. EMBO J. 2000 Jul 3;19(13):3192-203. doi: 10.1093/emboj/19.13.3192. EMBO J. 2000. PMID: 10880433 Free PMC article.

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