Johnson Z - Search Results

1

Identification of the glycosaminoglycan binding site of the CC chemokine, MCP-1: implications for structure and function in vivo.

Lau EK, Paavola CD, Johnson Z, Gaudry JP, Geretti E, Borlat F, Kungl AJ, Proudfoot AE, Handel TM. Lau EK, et al. Among authors: johnson z. J Biol Chem. 2004 May 21;279(21):22294-305. doi: 10.1074/jbc.M311224200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15033992 Free article.

2

Regulation of protein function by glycosaminoglycans--as exemplified by chemokines.

Handel TM, Johnson Z, Crown SE, Lau EK, Proudfoot AE. Handel TM, et al. Among authors: johnson z. Annu Rev Biochem. 2005;74:385-410. doi: 10.1146/annurev.biochem.72.121801.161747. Annu Rev Biochem. 2005. PMID: 15952892 Review.

3

Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.

Severin IC, Gaudry JP, Johnson Z, Kungl A, Jansma A, Gesslbauer B, Mulloy B, Power C, Proudfoot AE, Handel T. Severin IC, et al. Among authors: johnson z. J Biol Chem. 2010 Jun 4;285(23):17713-24. doi: 10.1074/jbc.M109.082552. Epub 2010 Apr 2. J Biol Chem. 2010. PMID: 20363748 Free PMC article.

4

Glycosaminoglycan binding and oligomerization are essential for the in vivo activity of certain chemokines.

Proudfoot AE, Handel TM, Johnson Z, Lau EK, LiWang P, Clark-Lewis I, Borlat F, Wells TN, Kosco-Vilbois MH. Proudfoot AE, et al. Among authors: johnson z. Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1885-90. doi: 10.1073/pnas.0334864100. Epub 2003 Feb 5. Proc Natl Acad Sci U S A. 2003. PMID: 12571364 Free PMC article.

5

Interaction of chemokines and glycosaminoglycans: a new twist in the regulation of chemokine function with opportunities for therapeutic intervention.

Johnson Z, Proudfoot AE, Handel TM. Johnson Z, et al. Cytokine Growth Factor Rev. 2005 Dec;16(6):625-36. doi: 10.1016/j.cytogfr.2005.04.006. Epub 2005 Jun 28. Cytokine Growth Factor Rev. 2005. PMID: 15990353 Review.

6

The X-ray structure of RANTES: heparin-derived disaccharides allows the rational design of chemokine inhibitors.

Shaw JP, Johnson Z, Borlat F, Zwahlen C, Kungl A, Roulin K, Harrenga A, Wells TN, Proudfoot AE. Shaw JP, et al. Among authors: johnson z. Structure. 2004 Nov;12(11):2081-93. doi: 10.1016/j.str.2004.08.014. Structure. 2004. PMID: 15530372 Free article.

7

An engineered monomer of CCL2 has anti-inflammatory properties emphasizing the importance of oligomerization for chemokine activity in vivo.

Handel TM, Johnson Z, Rodrigues DH, Dos Santos AC, Cirillo R, Muzio V, Riva S, Mack M, Déruaz M, Borlat F, Vitte PA, Wells TN, Teixeira MM, Proudfoot AE. Handel TM, et al. Among authors: johnson z. J Leukoc Biol. 2008 Oct;84(4):1101-8. doi: 10.1189/jlb.0108061. Epub 2008 Jul 28. J Leukoc Biol. 2008. PMID: 18662971 Free PMC article.

8

The basic residue cluster (55)KKWVR(59) in CCL5 is required for in vivo biologic function.

Segerer S, Johnson Z, Rek A, Baltus T, von Hundelshausen P, Kungl AJ, Proudfoot AE, Weber C, Nelson PJ. Segerer S, et al. Among authors: johnson z. Mol Immunol. 2009 Aug;46(13):2533-8. doi: 10.1016/j.molimm.2009.05.015. Epub 2009 Jun 12. Mol Immunol. 2009. PMID: 19524301

9

Glycosaminoglycan Interactions with Chemokines Add Complexity to a Complex System.

Proudfoot AEI, Johnson Z, Bonvin P, Handel TM. Proudfoot AEI, et al. Among authors: johnson z. Pharmaceuticals (Basel). 2017 Aug 9;10(3):70. doi: 10.3390/ph10030070. Pharmaceuticals (Basel). 2017. PMID: 28792472 Free PMC article. Review.

10

Antibody Neutralization of CXCL10 in Vivo Is Dependent on Binding to Free and Not Endothelial-bound Chemokine: IMPLICATIONS FOR THE DESIGN OF A NEW GENERATION OF ANTI-CHEMOKINE THERAPEUTIC ANTIBODIES.

Bonvin P, Gueneau F, Buatois V, Charreton-Galby M, Lasch S, Messmer M, Christen U, Luster AD, Johnson Z, Ferlin W, Kosco-Vilbois M, Proudfoot A, Fischer N. Bonvin P, et al. Among authors: johnson z. J Biol Chem. 2017 Mar 10;292(10):4185-4197. doi: 10.1074/jbc.M116.745877. Epub 2017 Jan 30. J Biol Chem. 2017. PMID: 28154179 Free PMC article.

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