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668 results

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Acute myeloid leukemia with complex karyotypes and abnormal chromosome 21: Amplification discloses overexpression of APP, ETS2, and ERG genes.
Baldus CD, Liyanarachchi S, Mrózek K, Auer H, Tanner SM, Guimond M, Ruppert AS, Mohamed N, Davuluri RV, Caligiuri MA, Bloomfield CD, de la Chapelle A. Baldus CD, et al. Among authors: de la chapelle a. Proc Natl Acad Sci U S A. 2004 Mar 16;101(11):3915-20. doi: 10.1073/pnas.0400272101. Epub 2004 Mar 8. Proc Natl Acad Sci U S A. 2004. PMID: 15007164 Free PMC article.
Overexpression of the ETS-related gene, ERG, predicts a worse outcome in acute myeloid leukemia with normal karyotype: a Cancer and Leukemia Group B study.
Marcucci G, Baldus CD, Ruppert AS, Radmacher MD, Mrózek K, Whitman SP, Kolitz JE, Edwards CG, Vardiman JW, Powell BL, Baer MR, Moore JO, Perrotti D, Caligiuri MA, Carroll AJ, Larson RA, de la Chapelle A, Bloomfield CD. Marcucci G, et al. Among authors: de la chapelle a. J Clin Oncol. 2005 Dec 20;23(36):9234-42. doi: 10.1200/JCO.2005.03.6137. Epub 2005 Nov 7. J Clin Oncol. 2005. PMID: 16275934
Heritable polymorphism predisposes to high BAALC expression in acute myeloid leukemia.
Eisfeld AK, Marcucci G, Liyanarachchi S, Döhner K, Schwind S, Maharry K, Leffel B, Döhner H, Radmacher MD, Bloomfield CD, Tanner SM, de la Chapelle A. Eisfeld AK, et al. Among authors: de la chapelle a. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6668-73. doi: 10.1073/pnas.1203756109. Epub 2012 Apr 9. Proc Natl Acad Sci U S A. 2012. PMID: 22493267 Free PMC article.
The polymorphism rs944289 predisposes to papillary thyroid carcinoma through a large intergenic noncoding RNA gene of tumor suppressor type.
Jendrzejewski J, He H, Radomska HS, Li W, Tomsic J, Liyanarachchi S, Davuluri RV, Nagy R, de la Chapelle A. Jendrzejewski J, et al. Among authors: de la chapelle a. Proc Natl Acad Sci U S A. 2012 May 29;109(22):8646-51. doi: 10.1073/pnas.1205654109. Epub 2012 May 14. Proc Natl Acad Sci U S A. 2012. PMID: 22586128 Free PMC article.
Gene expression profiling of isogenic cells with different TP53 gene dosage reveals numerous genes that are affected by TP53 dosage and identifies CSPG2 as a direct target of p53.
Yoon H, Liyanarachchi S, Wright FA, Davuluri R, Lockman JC, de la Chapelle A, Pellegata NS. Yoon H, et al. Among authors: de la chapelle a. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15632-7. doi: 10.1073/pnas.242597299. Epub 2002 Nov 15. Proc Natl Acad Sci U S A. 2002. PMID: 12438652 Free PMC article.
BAALC expression predicts clinical outcome of de novo acute myeloid leukemia patients with normal cytogenetics: a Cancer and Leukemia Group B Study.
Baldus CD, Tanner SM, Ruppert AS, Whitman SP, Archer KJ, Marcucci G, Caligiuri MA, Carroll AJ, Vardiman JW, Powell BL, Allen SL, Moore JO, Larson RA, Kolitz JE, de la Chapelle A, Bloomfield CD. Baldus CD, et al. Among authors: de la chapelle a. Blood. 2003 Sep 1;102(5):1613-8. doi: 10.1182/blood-2003-02-0359. Epub 2003 May 15. Blood. 2003. PMID: 12750167 Free article. Clinical Trial.
BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia.
Tanner SM, Austin JL, Leone G, Rush LJ, Plass C, Heinonen K, Mrózek K, Sill H, Knuutila S, Kolitz JE, Archer KJ, Caligiuri MA, Bloomfield CD, de La Chapelle A. Tanner SM, et al. Among authors: de la chapelle a. Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13901-6. doi: 10.1073/pnas.241525498. Epub 2001 Nov 13. Proc Natl Acad Sci U S A. 2001. PMID: 11707601 Free PMC article.
Mutational landscape and clinical outcome of patients with de novo acute myeloid leukemia and rearrangements involving 11q23/KMT2A.
Bill M, Mrózek K, Kohlschmidt J, Eisfeld AK, Walker CJ, Nicolet D, Papaioannou D, Blachly JS, Orwick S, Carroll AJ, Kolitz JE, Powell BL, Stone RM, de la Chapelle A, Byrd JC, Bloomfield CD. Bill M, et al. Among authors: de la chapelle a. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26340-26346. doi: 10.1073/pnas.2014732117. Epub 2020 Oct 5. Proc Natl Acad Sci U S A. 2020. PMID: 33020282 Free PMC article.
668 results