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Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells.
Estrov Z, Shishodia S, Faderl S, Harris D, Van Q, Kantarjian HM, Talpaz M, Aggarwal BB. Estrov Z, et al. Among authors: aggarwal bb. Blood. 2003 Aug 1;102(3):987-95. doi: 10.1182/blood-2002-11-3550. Epub 2003 Apr 10. Blood. 2003. PMID: 12689943 Free article.
Nuclear factor-kappaB and STAT3 are constitutively active in CD138+ cells derived from multiple myeloma patients, and suppression of these transcription factors leads to apoptosis.
Bharti AC, Shishodia S, Reuben JM, Weber D, Alexanian R, Raj-Vadhan S, Estrov Z, Talpaz M, Aggarwal BB. Bharti AC, et al. Among authors: aggarwal bb. Blood. 2004 Apr 15;103(8):3175-84. doi: 10.1182/blood-2003-06-2151. Epub 2003 Dec 18. Blood. 2004. PMID: 15070700 Free article.
Nuclear factor-kappaB: a friend or a foe in cancer?
Shishodia S, Aggarwal BB. Shishodia S, et al. Among authors: aggarwal bb. Biochem Pharmacol. 2004 Sep 15;68(6):1071-80. doi: 10.1016/j.bcp.2004.04.026. Biochem Pharmacol. 2004. PMID: 15313403 Review.
Ectopic expression of protein-tyrosine kinase Bcr-Abl suppresses tumor necrosis factor (TNF)-induced NF-kappa B activation and IkappaBalpha phosphorylation. Relationship with down-regulation of TNF receptors.
Mukhopadhyay A, Shishodia S, Suttles J, Brittingham K, Lamothe B, Nimmanapalli R, Bhalla KN, Aggarwal BB. Mukhopadhyay A, et al. Among authors: aggarwal bb. J Biol Chem. 2002 Aug 23;277(34):30622-8. doi: 10.1074/jbc.M204748200. Epub 2002 Jun 11. J Biol Chem. 2002. PMID: 12060665 Free article.
658 results