An antiviral peptide inhibitor that is active against picornavirus 2A proteinases but not cellular caspases.
Deszcz L, Cencic R, Sousa C, Kuechler E, Skern T.
Deszcz L, et al. Among authors: kuechler e.
J Virol. 2006 Oct;80(19):9619-27. doi: 10.1128/JVI.00612-06.
J Virol. 2006.
PMID: 16973565
Free PMC article.
We have recently shown that the general caspase inhibitor zVAD.fmk inhibits not only caspases, but also the 2Apro of human rhinoviruses (HRVs) (L. Deszcz, J. Seipelt, E. Vassilieva, A. Roetzer, and E. Kuechler, FEBS Lett. 560:51-55, 2004). ...
We have recently shown that the general caspase inhibitor zVAD.fmk inhibits not only caspases, but also the 2Apro of human rhinoviruses (HRV …