Maddon PJ - Search Results

1

Treatment of advanced human immunodeficiency virus type 1 disease with the viral entry inhibitor PRO 542.

Jacobson JM, Israel RJ, Lowy I, Ostrow NA, Vassilatos LS, Barish M, Tran DN, Sullivan BM, Ketas TJ, O'Neill TJ, Nagashima KA, Huang W, Petropoulos CJ, Moore JP, Maddon PJ, Olson WC. Jacobson JM, et al. Among authors: maddon pj. Antimicrob Agents Chemother. 2004 Feb;48(2):423-9. doi: 10.1128/AAC.48.2.423-429.2004. Antimicrob Agents Chemother. 2004. PMID: 14742190 Free PMC article. Clinical Trial.

2

Potent antiviral synergy between monoclonal antibody and small-molecule CCR5 inhibitors of human immunodeficiency virus type 1.

Murga JD, Franti M, Pevear DC, Maddon PJ, Olson WC. Murga JD, et al. Among authors: maddon pj. Antimicrob Agents Chemother. 2006 Oct;50(10):3289-96. doi: 10.1128/AAC.00699-06. Antimicrob Agents Chemother. 2006. PMID: 17005807 Free PMC article.

3

Single-dose safety, pharmacology, and antiviral activity of the human immunodeficiency virus (HIV) type 1 entry inhibitor PRO 542 in HIV-infected adults.

Jacobson JM, Lowy I, Fletcher CV, O'Neill TJ, Tran DN, Ketas TJ, Trkola A, Klotman ME, Maddon PJ, Olson WC, Israel RJ. Jacobson JM, et al. Among authors: maddon pj. J Infect Dis. 2000 Jul;182(1):326-9. doi: 10.1086/315698. Epub 2000 Jun 30. J Infect Dis. 2000. PMID: 10882617 Clinical Trial.

4

Human immunodeficiency virus type 1 entry inhibitors PRO 542 and T-20 are potently synergistic in blocking virus-cell and cell-cell fusion.

Nagashima KA, Thompson DA, Rosenfield SI, Maddon PJ, Dragic T, Olson WC. Nagashima KA, et al. Among authors: maddon pj. J Infect Dis. 2001 Apr 1;183(7):1121-5. doi: 10.1086/319284. Epub 2001 Mar 8. J Infect Dis. 2001. PMID: 11237840

5

Resistance to HIV-1 entry inhibitors.

Olson WC, Maddon PJ. Olson WC, et al. Among authors: maddon pj. Curr Drug Targets Infect Disord. 2003 Dec;3(4):283-94. doi: 10.2174/1568005033481015. Curr Drug Targets Infect Disord. 2003. PMID: 14754430 Review.

6

Phase 2a study of the CCR5 monoclonal antibody PRO 140 administered intravenously to HIV-infected adults.

Jacobson JM, Lalezari JP, Thompson MA, Fichtenbaum CJ, Saag MS, Zingman BS, D'Ambrosio P, Stambler N, Rotshteyn Y, Marozsan AJ, Maddon PJ, Morris SA, Olson WC. Jacobson JM, et al. Among authors: maddon pj. Antimicrob Agents Chemother. 2010 Oct;54(10):4137-42. doi: 10.1128/AAC.00086-10. Epub 2010 Jul 26. Antimicrob Agents Chemother. 2010. PMID: 20660677 Free PMC article. Clinical Trial.

7

Differential inhibition of human immunodeficiency virus type 1 fusion, gp120 binding, and CC-chemokine activity by monoclonal antibodies to CCR5.

Olson WC, Rabut GE, Nagashima KA, Tran DN, Anselma DJ, Monard SP, Segal JP, Thompson DA, Kajumo F, Guo Y, Moore JP, Maddon PJ, Dragic T. Olson WC, et al. Among authors: maddon pj. J Virol. 1999 May;73(5):4145-55. doi: 10.1128/JVI.73.5.4145-4155.1999. J Virol. 1999. PMID: 10196311 Free PMC article.

8

Potent, broad-spectrum inhibition of human immunodeficiency virus type 1 by the CCR5 monoclonal antibody PRO 140.

Trkola A, Ketas TJ, Nagashima KA, Zhao L, Cilliers T, Morris L, Moore JP, Maddon PJ, Olson WC. Trkola A, et al. Among authors: maddon pj. J Virol. 2001 Jan;75(2):579-88. doi: 10.1128/JVI.75.2.579-588.2001. J Virol. 2001. PMID: 11134270 Free PMC article.

9

Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein.

Schülke N, Vesanen MS, Sanders RW, Zhu P, Lu M, Anselma DJ, Villa AR, Parren PW, Binley JM, Roux KH, Maddon PJ, Moore JP, Olson WC. Schülke N, et al. Among authors: maddon pj. J Virol. 2002 Aug;76(15):7760-76. doi: 10.1128/jvi.76.15.7760-7776.2002. J Virol. 2002. PMID: 12097589 Free PMC article.

10

Human immunodeficiency virus type 1 membrane fusion mediated by a laboratory-adapted strain and a primary isolate analyzed by resonance energy transfer.

Litwin V, Nagashima KA, Ryder AM, Chang CH, Carver JM, Olson WC, Alizon M, Hasel KW, Maddon PJ, Allaway GP. Litwin V, et al. Among authors: maddon pj. J Virol. 1996 Sep;70(9):6437-41. doi: 10.1128/JVI.70.9.6437-6441.1996. J Virol. 1996. PMID: 8709277 Free PMC article.

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