The molecular basis of RhoA specificity in the guanine nucleotide exchange factor PDZ-RhoGEF.
Oleksy A, Opaliński Ł, Derewenda U, Derewenda ZS, Otlewski J.
Oleksy A, et al.
J Biol Chem. 2006 Oct 27;281(43):32891-7. doi: 10.1074/jbc.M606220200. Epub 2006 Sep 5.
J Biol Chem. 2006.
PMID: 16954208
Free article.
Based on the recently solved crystal structure of the DH-PH tandem of PDZ-RhoGEF in complex with RhoA (Derewenda, U., Oleksy, A., Stevenson, A. S., Korczynska, J., Dauter, Z., Somlyo, A. ...We show that while Trp(58) of RhoA is intimately involved in t …
Based on the recently solved crystal structure of the DH-PH tandem of PDZ-RhoGEF in complex with RhoA (Derewenda, U., Oleksy, A …