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Increased atypical PKC activity in endurance-trained human skeletal muscle.
Nielsen JN, Frøsig C, Sajan MP, Miura A, Standaert ML, Graham DA, Wojtaszewski JF, Farese RV, Richter EA. Nielsen JN, et al. Among authors: standaert ml. Biochem Biophys Res Commun. 2003 Dec 26;312(4):1147-53. doi: 10.1016/j.bbrc.2003.11.041. Biochem Biophys Res Commun. 2003. PMID: 14651992 Clinical Trial.
Sorbitol activates atypical protein kinase C and GLUT4 glucose transporter translocation/glucose transport through proline-rich tyrosine kinase-2, the extracellular signal-regulated kinase pathway and phospholipase D.
Sajan MP, Bandyopadhyay G, Kanoh Y, Standaert ML, Quon MJ, Reed BC, Dikic I, Farese RV. Sajan MP, et al. Among authors: standaert ml. Biochem J. 2002 Mar 15;362(Pt 3):665-74. doi: 10.1042/0264-6021:3620665. Biochem J. 2002. PMID: 11879194 Free PMC article.
Knockout of PKC alpha enhances insulin signaling through PI3K.
Leitges M, Plomann M, Standaert ML, Bandyopadhyay G, Sajan MP, Kanoh Y, Farese RV. Leitges M, et al. Among authors: standaert ml. Mol Endocrinol. 2002 Apr;16(4):847-58. doi: 10.1210/mend.16.4.0809. Mol Endocrinol. 2002. PMID: 11923480
Insulin signaling and insulin sensitizing in muscle and liver of obese monkeys: peroxisome proliferator-activated receptor gamma agonist improves defective activation of atypical protein kinase C.
Ortmeyer HK, Sajan MP, Miura A, Kanoh Y, Rivas J, Li Y, Standaert ML, Ryan AS, Bodkin NL, Farese RV, Hansen BC. Ortmeyer HK, et al. Among authors: standaert ml. Antioxid Redox Signal. 2011 Jan 15;14(2):207-19. doi: 10.1089/ars.2010.3234. Epub 2010 Nov 23. Antioxid Redox Signal. 2011. PMID: 20518698 Free PMC article.
AICAR and metformin, but not exercise, increase muscle glucose transport through AMPK-, ERK-, and PDK1-dependent activation of atypical PKC.
Sajan MP, Bandyopadhyay G, Miura A, Standaert ML, Nimal S, Longnus SL, Van Obberghen E, Hainault I, Foufelle F, Kahn R, Braun U, Leitges M, Farese RV. Sajan MP, et al. Among authors: standaert ml. Am J Physiol Endocrinol Metab. 2010 Feb;298(2):E179-92. doi: 10.1152/ajpendo.00392.2009. Epub 2009 Nov 3. Am J Physiol Endocrinol Metab. 2010. PMID: 19887597 Free PMC article.
108 results