Forsyth CM - Search Results

1

Crystal structure of an invertebrate caspase.

Forsyth CM, Lemongello D, LaCount DJ, Friesen PD, Fisher AJ. Forsyth CM, et al. J Biol Chem. 2004 Feb 20;279(8):7001-8. doi: 10.1074/jbc.M312472200. Epub 2003 Nov 27. J Biol Chem. 2004. PMID: 14645217 Free article.

2

De novo design of an IL-4 antagonist and its structure at 1.9 A.

Laporte SL, Forsyth CM, Cunningham BC, Miercke LJ, Akhavan D, Stroud RM. Laporte SL, et al. Among authors: forsyth cm. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):1889-94. doi: 10.1073/pnas.0408890102. Epub 2005 Jan 31. Proc Natl Acad Sci U S A. 2005. PMID: 15684085 Free PMC article.

3

Fine and domain-level epitope mapping of botulinum neurotoxin type A neutralizing antibodies by yeast surface display.

Levy R, Forsyth CM, LaPorte SL, Geren IN, Smith LA, Marks JD. Levy R, et al. Among authors: forsyth cm. J Mol Biol. 2007 Jan 5;365(1):196-210. doi: 10.1016/j.jmb.2006.09.084. Epub 2006 Oct 3. J Mol Biol. 2007. PMID: 17059824 Free PMC article.

4

Sequence variation within botulinum neurotoxin serotypes impacts antibody binding and neutralization.

Smith TJ, Lou J, Geren IN, Forsyth CM, Tsai R, Laporte SL, Tepp WH, Bradshaw M, Johnson EA, Smith LA, Marks JD. Smith TJ, et al. Among authors: forsyth cm. Infect Immun. 2005 Sep;73(9):5450-7. doi: 10.1128/IAI.73.9.5450-5457.2005. Infect Immun. 2005. PMID: 16113261 Free PMC article.

5

Molecular evolution of antibody cross-reactivity for two subtypes of type A botulinum neurotoxin.

Garcia-Rodriguez C, Levy R, Arndt JW, Forsyth CM, Razai A, Lou J, Geren I, Stevens RC, Marks JD. Garcia-Rodriguez C, et al. Among authors: forsyth cm. Nat Biotechnol. 2007 Jan;25(1):107-16. doi: 10.1038/nbt1269. Epub 2006 Dec 17. Nat Biotechnol. 2007. PMID: 17173035

6

A structural perspective of the sequence variability within botulinum neurotoxin subtypes A1-A4.

Arndt JW, Jacobson MJ, Abola EE, Forsyth CM, Tepp WH, Marks JD, Johnson EA, Stevens RC. Arndt JW, et al. Among authors: forsyth cm. J Mol Biol. 2006 Sep 29;362(4):733-42. doi: 10.1016/j.jmb.2006.07.040. Epub 2006 Jul 27. J Mol Biol. 2006. PMID: 16938310

7

Neutralizing human monoclonal antibodies binding multiple serotypes of botulinum neurotoxin.

Garcia-Rodriguez C, Geren IN, Lou J, Conrad F, Forsyth C, Wen W, Chakraborti S, Zao H, Manzanarez G, Smith TJ, Brown J, Tepp WH, Liu N, Wijesuriya S, Tomic MT, Johnson EA, Smith LA, Marks JD. Garcia-Rodriguez C, et al. Protein Eng Des Sel. 2011 Mar;24(3):321-31. doi: 10.1093/protein/gzq111. Epub 2010 Dec 13. Protein Eng Des Sel. 2011. PMID: 21149386 Free PMC article.

8

Affinity maturation of human botulinum neurotoxin antibodies by light chain shuffling via yeast mating.

Lou J, Geren I, Garcia-Rodriguez C, Forsyth CM, Wen W, Knopp K, Brown J, Smith T, Smith LA, Marks JD. Lou J, et al. Among authors: forsyth cm. Protein Eng Des Sel. 2010 Apr;23(4):311-9. doi: 10.1093/protein/gzq001. Epub 2010 Feb 15. Protein Eng Des Sel. 2010. PMID: 20156888 Free PMC article.

9

Molecular evolution of antibody affinity for sensitive detection of botulinum neurotoxin type A.

Razai A, Garcia-Rodriguez C, Lou J, Geren IN, Forsyth CM, Robles Y, Tsai R, Smith TJ, Smith LA, Siegel RW, Feldhaus M, Marks JD. Razai A, et al. Among authors: forsyth cm. J Mol Biol. 2005 Aug 5;351(1):158-69. doi: 10.1016/j.jmb.2005.06.003. J Mol Biol. 2005. PMID: 16002090

10

Epitope and Fc-Mediated Cross-linking, but Not High Affinity, Are Critical for Antitumor Activity of CD137 Agonist Antibody with Reduced Liver Toxicity.

Ho SK, Xu Z, Thakur A, Fox M, Tan SS, DiGiammarino E, Zhou L, Sho M, Cairns B, Zhao V, Xiong M, Samayoa J, Forsyth CM, Powers DB, Chao DT, Hollenbaugh D, Alvarez HM, Akamatsu Y. Ho SK, et al. Among authors: forsyth cm. Mol Cancer Ther. 2020 Apr;19(4):1040-1051. doi: 10.1158/1535-7163.MCT-19-0608. Epub 2020 Jan 23. Mol Cancer Ther. 2020. PMID: 31974274

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