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Mice with defects in HB-EGF ectodomain shedding show severe developmental abnormalities.
Yamazaki S, Iwamoto R, Saeki K, Asakura M, Takashima S, Yamazaki A, Kimura R, Mizushima H, Moribe H, Higashiyama S, Endoh M, Kaneda Y, Takagi S, Itami S, Takeda N, Yamada G, Mekada E. Yamazaki S, et al. Among authors: takeda n. J Cell Biol. 2003 Nov 10;163(3):469-75. doi: 10.1083/jcb.200307035. Epub 2003 Nov 3. J Cell Biol. 2003. PMID: 14597776 Free PMC article.
Hepatocyte growth factor activator inhibitor type 1 (HAI-1) is required for branching morphogenesis in the chorioallantoic placenta.
Tanaka H, Nagaike K, Takeda N, Itoh H, Kohama K, Fukushima T, Miyata S, Uchiyama S, Uchinokura S, Shimomura T, Miyazawa K, Kitamura N, Yamada G, Kataoka H. Tanaka H, et al. Among authors: takeda n. Mol Cell Biol. 2005 Jul;25(13):5687-98. doi: 10.1128/MCB.25.13.5687-5698.2005. Mol Cell Biol. 2005. PMID: 15964823 Free PMC article.
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice.
Kuroda N, Mitani T, Takeda N, Ishimaru N, Arakaki R, Hayashi Y, Bando Y, Izumi K, Takahashi T, Nomura T, Sakaguchi S, Ueno T, Takahama Y, Uchida D, Sun S, Kajiura F, Mouri Y, Han H, Matsushima A, Yamada G, Matsumoto M. Kuroda N, et al. Among authors: takeda n. J Immunol. 2005 Feb 15;174(4):1862-70. doi: 10.4049/jimmunol.174.4.1862. J Immunol. 2005. PMID: 15699112
Defect of hepatocyte growth factor activator inhibitor type 1/serine protease inhibitor, Kunitz type 1 (Hai-1/Spint1) leads to ichthyosis-like condition and abnormal hair development in mice.
Nagaike K, Kawaguchi M, Takeda N, Fukushima T, Sawaguchi A, Kohama K, Setoyama M, Kataoka H. Nagaike K, et al. Among authors: takeda n. Am J Pathol. 2008 Nov;173(5):1464-75. doi: 10.2353/ajpath.2008.071142. Epub 2008 Oct 2. Am J Pathol. 2008. PMID: 18832587 Free PMC article.
Complete antithrombin deficiency in mice results in embryonic lethality.
Ishiguro K, Kojima T, Kadomatsu K, Nakayama Y, Takagi A, Suzuki M, Takeda N, Ito M, Yamamoto K, Matsushita T, Kusugami K, Muramatsu T, Saito H. Ishiguro K, et al. Among authors: takeda n. J Clin Invest. 2000 Oct;106(7):873-8. doi: 10.1172/JCI10489. J Clin Invest. 2000. PMID: 11018075 Free PMC article.
2,061 results