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Transmembrane helix predictions revisited.
Chen CP, Kernytsky A, Rost B. Chen CP, et al. Among authors: kernytsky a. Protein Sci. 2002 Dec;11(12):2774-91. doi: 10.1110/ps.0214502. Protein Sci. 2002. PMID: 12441377 Free PMC article.
Membrane protein prediction methods.
Punta M, Forrest LR, Bigelow H, Kernytsky A, Liu J, Rost B. Punta M, et al. Among authors: kernytsky a. Methods. 2007 Apr;41(4):460-74. doi: 10.1016/j.ymeth.2006.07.026. Methods. 2007. PMID: 17367718 Free PMC article. Review.
Static benchmarking of membrane helix predictions.
Kernytsky A, Rost B. Kernytsky A, et al. Nucleic Acids Res. 2003 Jul 1;31(13):3642-4. doi: 10.1093/nar/gkg532. Nucleic Acids Res. 2003. PMID: 12824384 Free PMC article.
Evaluation of Homology-Independent CRISPR-Cas9 Off-Target Assessment Methods.
Chaudhari HG, Penterman J, Whitton HJ, Spencer SJ, Flanagan N, Lei Zhang MC, Huang E, Khedkar AS, Toomey JM, Shearer CA, Needham AW, Ho TW, Kulman JD, Cradick TJ, Kernytsky A. Chaudhari HG, et al. Among authors: kernytsky a. CRISPR J. 2020 Dec;3(6):440-453. doi: 10.1089/crispr.2020.0053. CRISPR J. 2020. PMID: 33346710 Free PMC article.
CRISPR-Cas9 Gene Editing for Sickle Cell Disease and β-Thalassemia.
Frangoul H, Altshuler D, Cappellini MD, Chen YS, Domm J, Eustace BK, Foell J, de la Fuente J, Grupp S, Handgretinger R, Ho TW, Kattamis A, Kernytsky A, Lekstrom-Himes J, Li AM, Locatelli F, Mapara MY, de Montalembert M, Rondelli D, Sharma A, Sheth S, Soni S, Steinberg MH, Wall D, Yen A, Corbacioglu S. Frangoul H, et al. Among authors: kernytsky a. N Engl J Med. 2021 Jan 21;384(3):252-260. doi: 10.1056/NEJMoa2031054. Epub 2020 Dec 5. N Engl J Med. 2021. PMID: 33283989 Clinical Trial.
A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model.
Wang F, Travins J, Lin Z, Si Y, Chen Y, Powe J, Murray S, Zhu D, Artin E, Gross S, Santiago S, Steadman M, Kernytsky A, Straley K, Lu C, Pop A, Struys EA, Jansen EE, Salomons GS, David MD, Quivoron C, Penard-Lacronique V, Regan KS, Liu W, Dang L, Yang H, Silverman L, Agresta S, Dorsch M, Biller S, Yen K, Cang Y, Su SM, Jin S. Wang F, et al. Among authors: kernytsky a. J Inherit Metab Dis. 2016 Nov;39(6):807-820. doi: 10.1007/s10545-016-9960-y. Epub 2016 Jul 28. J Inherit Metab Dis. 2016. PMID: 27469509 Free PMC article.
MTAP Deletions in Cancer Create Vulnerability to Targeting of the MAT2A/PRMT5/RIOK1 Axis.
Marjon K, Cameron MJ, Quang P, Clasquin MF, Mandley E, Kunii K, McVay M, Choe S, Kernytsky A, Gross S, Konteatis Z, Murtie J, Blake ML, Travins J, Dorsch M, Biller SA, Marks KM. Marjon K, et al. Among authors: kernytsky a. Cell Rep. 2016 Apr 19;15(3):574-587. doi: 10.1016/j.celrep.2016.03.043. Epub 2016 Apr 7. Cell Rep. 2016. PMID: 27068473 Free article.
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